… Cytokinestorm syndrome (CSS) is an acute complication in ~2% of KD patients; however, the incidence is likely underestimated as many clinical … KD with CSS deserves consideration. …
R Stebbings, L Findlay, C Edwards… - The Journal of …, 2007 - journals.aai.org
… Group on Phase One Clinical Trials, as well as in-house considerations, a wider investigation of TGN1412, relevant to its safety evaluation and the safety of clinical trials, was conducted …
JK GUPTA - International Journal of Pharmaceutical …, 2021 - search.ebscohost.com
… Incidences of cytokinestorm are generally inculpated on the emergence of acute clinical symptoms. The most prevalent symptoms are acute bronchopneumonia, substantial pulmonary …
P Mehta, RQ Cron, J Hartwell, JJ Manson… - The Lancet …, 2020 - thelancet.com
… RQC is co-principal investigator of an investigator initiated clinical trial funded by Swedish Orphan Biovitrum (SOBI), is on the advisory board for SOBI (<US$5000), and is on the clinical …
… Elevated cytokines and suppressed immune responses have been hypothesized to set off a cytokinestorm, contributing to ARDS, multiple-organ failure and, in the most severe cases, …
… immune mediated effects such as cytokinestorm, make medical management more … of clinical success, and will be discussed in this section. Several antivirals approved for other clinical …
P Asrani, MI Hassan - Molecular and Cellular Biochemistry, 2021 - Springer
… cytokinestorm (CS) production. This paper highlights the different stages of viral-mediated inflammatory responses in the host respiratory system. Previously, known anti-inflammatory …
… To describe this phenomenon, the term “cytokinestorm” has … cytokinestorm is considered as the result of the disrupted immune response to the initial insult, the range of the clinical …
… the available clinical data in order to provide useful information to clinicians about the … shock and, more recently, to the cytokinestorm and hyper-inflammation developing in severe …