Single dose tocilizumab for COVID‐19 associated cytokine storm syndrome: Less is more

NW Boone, DJAR Moes, S Ramiro… - … journal of clinical …, 2023 - Wiley Online Library
IL-6 … ] At the clinical introduction of TCZ in the treatment of COVID-19 induced CSS its
non-labelled application sparked controversy.[10] In accordance with our findings based on clinical

[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
… responses of ARDS during cytokine storms in COVID-19 … characteristics and mechanisms of
cytokine storms, host responses… little clinical data available in regard to evidence for cytokine

[HTML][HTML] Exploring the utility of extracellular vesicles in ameliorating viral infection-associated inflammation, cytokine storm and tissue damage

N Pillalamarri, G Ren, L Khan, A Ullah, S Jonnakuti… - Translational …, 2021 - Elsevier
… obtain EVs with specific (viral) surface proteins that is able to target lung cells and how to
scale up the production of EV-based vaccines so that we have sufficient quantities for clinical

[HTML][HTML] Lessons learned to date on COVID-19 hyperinflammatory syndrome: considerations for interventions to mitigate SARS-CoV-2 viral infection and detrimental …

M Cardone, M Yano, AS Rosenberg… - Frontiers in …, 2020 - frontiersin.org
… release of cytokines, chemokines and growth factors. This cytokine storm creates an …
progression of the clinical studies using these products in COVID-19 (if clinical trials were registered …

[HTML][HTML] Consideration of severe coronavirus disease 2019 as viral sepsis and potential use of immune checkpoint inhibitors

Z Odabasi, I Cinel - Critical care explorations, 2020 - journals.lww.com
… Taking into consideration the multisystemic clinical and … term to describe the whole clinical
picture. The most significant … be effective in the treatment of cytokine storm, but some patients …

Induction of ketosis as a potential therapeutic option to limit hyperglycemia and prevent cytokine storm in COVID-19

SG Sukkar, M Bassetti - Nutrition, 2020 - Elsevier
clinical manifestation of COVID-19 and require hospitalization in intensive care units may
have a cytokine storm … According to this consideration, it might be more beneficial to start the …

Excitotoxicity (immunoexcitotoxicity) as a critical component of the cytokine storm reaction in pulmonary viral infections, including SARS-CoV-2

RL Blaylock - International Journal of Vaccine Theory, Practice, and …, 2021 - ijvtpr.com
clinical deterioration and eventual death in these patients. While most studies have attributed
the pathological damage to the lung to be primarily due to high levels of cytokinescytokine

Pharmacotherapeutics for cytokine storm in COVID-19

R Pal, MJ Chaudhary - Stem Cells, 2024 - Elsevier
considerations should be noted between COVID-19- associated CS and many other CS
disorders. Cytokine storm … block individual cytokines to achieve the desired clinical benefit given …

[HTML][HTML] COVID-19 disease, women's predominant non-heparin vaccine-induced thrombotic thrombocytopenia and Kounis Syndrome: A passepartout cytokine storm …

NG Kounis, I Koniari, C De Gregorio… - Biomedicines, 2021 - mdpi.com
… immune cells, inducing a cytokine storm [7]. Severe … cytokine storm syndrome, leading to
increased risk of mortality. The characteristics and clinical manifestations of this cytokine storm

[HTML][HTML] Novel paediatric presentation of COVID-19 with ARDS and cytokine storm syndrome without respiratory symptoms

CE Pain, S Felsenstein, G Cleary, S Mayell… - The Lancet …, 2020 - thelancet.com
… Secondary multisystem inflammatory disease or cytokine storm syndrome was diagnosed
based on clinical symptoms, lymphopenia, anaemia, thrombocytopenia, increased acute-…