SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

A Tsatsakis, D Calina, L Falzone, D Petrakis… - Food and Chemical …, 2020 - Elsevier
… Moreover, SARS-CoV-2 can cause central and peripheral neurological manifestations, … of
contracting the SARS-CoV-2 virus. Considering the multitude of clinical symptoms of COVID-19…

The thrilling journey of SARS-CoV-2 into the intestine: from pathogenesis to future clinical implications

F Scaldaferri, G Ianiro, G Privitera… - Inflammatory Bowel …, 2020 - academic.oup.com
… In this review, we focus on the current evidence of the relationship between SARS-CoV-2
and the gastrointestinal system; we outline the main implications on the management of …

[HTML][HTML] Emerging SARS-CoV-2 variants: genetic variability and clinical implications

A Dubey, S Choudhary, P Kumar, S Tomar - Current microbiology, 2022 - Springer
… or deletions in the S protein of SARS-CoV-2 suggests that the … to ameliorate further spread
of SARS-CoV-2 infections. Failure to … newly identified variants of SARS-CoV-2, providing …

[HTML][HTML] SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications

S Gross, C Jahn, S Cushman, C Baer… - Journal of molecular and …, 2020 - Elsevier
… In the following part of this review, we will highlight potentially connective mechanisms of
SARS-CoV-2 and the dysregulated presentation of ACE2 with the described clinical features in …

Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week

A Brojakowska, J Narula, R Shimony… - Journal of the American …, 2020 - jacc.org
coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting
enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was … in SARS-CoV

Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications

NM Habashi, L Camporota… - Journal of applied …, 2021 - journals.physiology.org
The worldwide pandemic caused by the SARS-CoV-2 virus has resulted in over 84,407,000
cases, with over 1,800,000 deaths when this paper was submitted, with comorbidities such …

SARS-CoV-2 E484K mutation narrative review: epidemiology, immune escape, clinical implications, and future considerations

WT Yang, WH Huang, TL Liao, TH Hsiao… - Infection and Drug …, 2022 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly over the
world and claimed million lives. The virus evolves constantly, and a swarm of mutants is a now …

An overview of coronaviruses including the SARS-2 coronavirus–molecular biology, epidemiology and clinical implications

D Kaul - Current medicine research and practice, 2020 - Elsevier
… betacoronavirus or severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has
spread … syndrome (MERS) coronavirus and the recently discovered SARS CoV-2. The gamma …

[HTML][HTML] More than pneumonia: distinctive features of SARS-CoV-2 infection. From autopsy findings to clinical implications: a systematic review

S D'Errico, M Zanon, M Montanaro, D Radaelli… - Microorganisms, 2020 - mdpi.com
… in urine observed in clinical studies and suggest a direct virulence of SARS-CoV-2. Acute
(… A possible role of CD147 in SARS-CoV-2 infection of renal epithelial tubular cells has been …

[HTML][HTML] Clinical implications of SARS-CoV-2 infection in the viable preterm period

M Gulersen, MJ Blitz, B Rochelson… - American Journal of …, 2020 - thieme-connect.com
… regarding clinical outcomes of SARS-CoV-2 infection in the viable preterm period. Our
data are reassuring, suggesting that the risk of preterm delivery during infection with SARS-CoV-2 …