… their implications in contemporary prostate cancer clinical care, as well as current efforts
in therapeutic targeting of AR-Vs aiming to overcome resistance to novel hormonal therapies. …

… Here, we discuss the significance of BCSC membrane biomarkers as potential prognostic
and therapeutic targets, reviewing the CSC-targeting therapies under clinical trials for breast …

… by therapies targeting CSC will require an in-depth understanding of the molecular
mechanisms governing CSC self renewal, differentiation, and escape from conventional therapy. …

Genetic abnormalities have been conventionally considered as hallmarks of cancer.
However, studies over the past decades have demonstrated that epigenetic regulation also …

… Given its role in NO synthesis, gene therapy targeted toward up regulations of eNOS …
when devising the strategy for gene therapy targeting eNOS expression to avoid unwanted …

… highlights a number of important new targets for therapeutic intervention. In contrast to earlier
… lead to the identification of a number of new therapeutic targets for tumour management. …

… therapeutics targeting the basic defect in people with CF. In this review, we focus on recent
advances in our understanding of the molecular defects caused by different classes of CFTR …

… clinical trials based on c‐MET molecular targets result in good safety profile and represent a
promising therapeutic … or in combination with other target drugs. Conclusion. The list of cell …

Extensive cancer research in the past few decades has identified the existence of a rare
subpopulation of stem cells in the grove of cancer cells. These cells are known as the cancer …

… clinical trials of combination therapies targeted to specific groups of patients, but will also help
discover new therapeutic targets … Nevertheless, clinical development may still be limited by …