Experimental human challenge infections can accelerate clinical malaria vaccine development

RW Sauerwein, M Roestenberg… - Nature Reviews …, 2011 - nature.com
… , should human malaria challenge models be more widely used to reduce … malaria challenge
models and provides future perspectives for these models in malaria vaccine development. …

Advances and challenges in malaria vaccine development

PD Crompton, SK Pierce… - The Journal of clinical …, 2010 - Am Soc Clin Investig
… a highly effective vaccine is in … malaria vaccine development has barely reached 25% of
the approximately $684 million invested in the development of a still-elusive HIV/AIDS vaccine (8…

The path of malaria vaccine development: challenges and perspectives

C Arama, M Troye‐Blomberg - Journal of internal medicine, 2014 - Wiley Online Library
… There is great interest in developing new and better … recent strategies to develop efficient
malaria vaccines. … Malaria vaccine development is an active research area with enormous …

Extreme polymorphism in a vaccine antigen and risk of clinical malaria: implications for vaccine development

SL Takala, D Coulibaly, MA Thera… - Science translational …, 2009 - science.org
… The main target protein for vaccines currently in development is the highly variable apical …
This seems like bad news for malaria vaccine development, but additional data suggest a new …

Malaria vaccine developments

VS Moorthy, MF Good, AVS Hill - The lancet, 2004 - thelancet.com
… for other diseases are being evaluated first in malaria. We describe progress in malaria
vaccine development in the past 5 years: reasons for cautious optimism, the type of vaccine that …

A new landscape for malaria vaccine development

AJ Laurenson, MB Laurens - PLoS Pathogens, 2024 - journals.plos.org
malaria vaccines becoming available, how has this milestone influenced malaria vaccine
research and development … more about the current landscape of malaria vaccine development. …

[HTML][HTML] Update on the clinical development of candidate malaria vaccines

WR Ballou, M Arevalo-Herrera, D Carucci… - … Malaria II: What's New …, 2004 - ncbi.nlm.nih.gov
… profiles and clinical development plans that … development of malaria vaccine development,
focusing in particular on those candidate vaccines that will soon be or are currently in clinical

[HTML][HTML] Status of vaccine research and development of vaccines for malaria

AJ Birkett - Vaccine, 2016 - Elsevier
… The continued absence of financially lucrative, high-income markets to drive investment in
malaria vaccine development points to continued heavy reliance on public and philanthropic …

Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium

CH Coelho, JYA Doritchamou, I Zaidi, PE Duffy - npj Vaccines, 2017 - nature.com
Malaria Vaccine Symposium. In this meeting report, we highlight the progress on different
malaria vaccine … and genetic findings that may impact malaria vaccine responses and efficacy. …

Immune mechanisms in malaria: new insights in vaccine development

EM Riley, VA Stewart - Nature medicine, 2013 - nature.com
… requirements for malaria vaccines and the recent history of malaria vaccine development
and … We argue that rational design of more effective malaria vaccines will be accelerated by a …