… centre in Cambridge in 1994 presented a unique opportunity to study the effect of centre
care on the clinical outcome of cystic fibrosis. The absence of a cystic fibrosis centre within the …

… in children screened for cystic fibrosis than in those … clinical outcomes for children with cystic
fibrosis. For countries contemplating the introduction of neonatal screening for cystic fibrosis, …

Diagnosis of cystic fibrosis (CF), the most common life‐limiting recessive genetic condition
in the caucasian population, via NBS is now occurring in many regions of the world. There is …

… with poor clinical outcomes. Primary clinical outcomes in the original study included pulmonary
exacerbation rates, survival and lung function, and these same outcomes are presented …

… clinical outcomes and prognostic factors in different cohorts of subjects with CF. Our objectives
were to evaluate clinical outcomes … longitudinal changes in clinical scores, spirometry, 6-…

Background All 50 United States implemented newborn screening (NBS) for cystic fibrosis (CF)
by 2010. The purpose of this study was to evaluate trends over the decade when NBS …

… Our results suggest that higher BMI is associated with favorable clinical outcomes in
patients with CF. Both overweight and obesity are associated with clinically significantly better …

… aeruginosa from the lower airway was associated with subsequent decline in clinical
status, linear regression methods were used to assess the effect on clinical outcomes at age 3 …

… Our lung function and clinical outcome data verify these studies and add additional information
by examining a large population over an extended period of time. We have shown that …

… Treatment burden and depressive symptoms may become increasingly important clinical
outcome measures as more complex and time-consuming therapeutic regimens are added to …