[HTML][HTML] Mechanism of cytokine modulation of epithelial tight junction barrier

R Al-Sadi, M Boivin, T Ma - Frontiers in bioscience: a journal and …, 2009 - ncbi.nlm.nih.gov
… role in disruption of intestinal TJ barrier under a variety of clinically relevant conditions. …
Interestingly, IL-2 administration to sheep causes a severe capillary leak syndrome with …

Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

RM Rajani, J Ratelade, V Domenga-Denier… - Acta neuropathologica …, 2019 - Springer
… We chose fibrinogen as a marker of BBB leakage due to its relevance to WMLs – in a mouse
model of pericyte loss and BBB leakage, fibrinogen was suggested to be responsible for …

A material stress test study on occurrence of leakage and material failure of peritoneal dialysis (PD) catheters

M Klingele, M Carstens, L Baerens, MW Laschke… - Scientific Reports, 2021 - nature.com
… nor any leakage or barrier indulgence. Our … leakages of the PD catheter initiated our material
stress test idea in a laboratory setting. Only a simulation of the relevant and typical clinical

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice

E Camerer, JB Regard, I Cornelissen… - … Journal of clinical …, 2009 - Am Soc Clin Investig
… Sphingosine-1-phosphate (S1P) can regulate endothelial barrier function, but the … relevant.
Nonetheless, our finding that S1P signaling is important for resisting lethal responses to leak-…

Retinoic acid improves baseline barrier function and attenuates TNF-α-induced barrier leak in human bronchial epithelial cell culture model, 16HBE 14o

PJ Callaghan, E Rybakovsky, B Ferrick, S Thomas… - PLoS …, 2020 - journals.plos.org
… to 14 C-mannitol and 80% of the leak to 14 C-inulin. Interleukin-6-induced barrier leak was
… agent in minimizing airway barrier leak and as a therapeutic in preventing leak triggered by …

IFN‐β protects from vascular leakage via up‐regulation of CD73

J Kiss, GG Yegutkin, K Koskinen… - European journal of …, 2007 - Wiley Online Library
… Indirect ALI represents a completely different and clinically relevantleakage in CD73-deficient
animals. Thus, insufficient CD73 activity correlates with impaired endothelial barrier

Update on therapeutic strategy for esophageal anastomotic leak: A systematic literature review

F Hua, D Sun, X Zhao, X Song, W Yang - Thoracic Cancer, 2023 - Wiley Online Library
relevant clinical reports, good therapeutic effects have been achieved in both esophageal
gastric anastomotic leak and gastric staple line leak… quickly overcome the barrier. Endoluminal …

Disrupted barrier function through epithelial cell apoptosis

JD SCHULZKE, C Bojarski, S Zeissig… - Annals of the New …, 2006 - Wiley Online Library
… epithelial apoptoses are functionally relevant by raising four … leaks in the mucosal barrier
to molecules must be smaller than 1.2 nm. Neither bacteria nor viruses can penetrate the leaks

Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis

L Su, L Shen, DR Clayburgh, SC Nalle, EA Sullivan… - Gastroenterology, 2009 - Elsevier
… the impact of pathophysiologically relevant barrier dysfunction on mucosal homeostasis. …
that barrier defects result in antigen leakage, mucosal immune activation, and clinical disease. …

Quantification of adherens junction disruption and contiguous paracellular protein leak in human lung endothelial cells under septic conditions

L Wang, J Chung, SE Gill, S Mehta - Microcirculation, 2019 - Wiley Online Library
… greatest relevance to septic MOD is a loss of normal MVEC permeability barrier function, which
results in the leak … and MVEC dysfunction of direct clinical relevance in human sepsis and …