… blood–brain barrier, which is located at the level of the brain microvessels and represents the
largest interface between brain and blood, … The blood–brain barrier protects the brain from …

… in clinical and postmortem studies, summarize changes that lead to barrier leakage in patients
and highlight the clinical relevance of … Finally, we discuss clinical relevance and potential …

… of the blood–brain barrier (BBB) in the handling of brain L-… blood L-glutamate levels and
brain ISF L-glutamate levels. Finally we will discuss the possible clinical relevance of brain …

… Because the goal of this review is primarily to discuss the BBB in the context of clinically
relevant geriatric concerns, the interested reader is referred to excellent reviews pertaining to …

… blood–brain barrier dysfunction are diverse and may range from physical endothelial damage
in traumatic brain injury … Clinically, blood–brain barrier dysfunction is often detected using …

… The clinical relevance of these BBB changes during systemic inflammation are discussed
in the context of clinically-apparent syndromes such as sickness behaviour, delirium, and …

… period of time to the clinic to enhance chemotherapy of brain tumors. 6 The contributions in
… BBB and on its clinical relevance. The chapters on the blood-nerve and blood-ocular barriers …

… Finally, to test the pharmacodynamic relevance of the proposed … Our results show that early
blood–brain barrier pathology in the … of blood–brain barrier pathology as a clinically relevant …

… Research during the past decade has greatly extended our appreciation of the blood-brain
barrier (… For optimum application of imaging methods of the brain, clinicians should have a …

… Within the neurovascular unit (NVU), the blood–brain barrier (BBB) … the brain parenchyma
from peripheral blood and compartments. Increased BBB permeability is clinically relevant for …