… -CoV-2 infection in vivo. Our findings suggest the potential to develop XG014 as pan-β-CoV-…
protective vaccines against β-CoV-B and newly emerging SARS-CoV-2 variants of concern. …

… the closed (PDB ID: 6VXX) and open (PDB ID: 6VYB) states of the SARS-CoV-2 S protein
to investigate the conformational transition pathway and estimate conformational dynamics …

… is applicable to other β-coronaviruses, such as SARS-CoV and MERS-CoV, and might …
RBM is concealed in the closed conformation, we hypothesized that SARS-CoV-2 2P DS S …

… A number of SARS-CoV-2 … -CoV-2 Kappa and Beta variants in the open or transition state
for each variant at the resolution of 3.2–3.6 Å, revealing not only their unique conformational …

… differences [39] and established as β = 1. The differences between the ΔS vib values for …
mutant G614 we observe that for the closed conformation, the pattern tends towards negative …

… Further processing of the 320,000 closed conformation particles allowed us to obtain a …
closed conformation and a 3.0 Å electron potential map for the 1 RBD-up (one up) conformation (…

… the closed conformation of spike protein and potentially lead to a reduction in SARS-CoV-2 …
-3 PUFA could also bind to the closed conformation of spike protein and therefore, could …

… potent, immune responses than open spikes and that this is likely to include neutralizing
antibodies against conformational epitopes present in the closed conformation. We suggest that …

… protein in its closed conformation is probably more … closed conformation of the spike protein,
thus blocking its transition to an open state and locking the closed pre-fusion conformation, …

… conformation equilibrium between RBD(closed) and RBD(open). Suppose A denotes closed
conformation and B open conformation. … GB respectively in two conformations. Generally, if …