Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia

R Saggu, T Schumacher, F Gerich, C Rakers… - Acta neuropathologica …, 2016 - Springer
cognitive impairment is the second most common form of dementia. The pathogenic pathways
leading to vascular cognitive impairment … To model vascular cognitive impairment, we …

Metformin attenuates LPS-induced neuronal injury and cognitive impairments by blocking NF-κB pathway

C Zhou, B Peng, Z Qin, W Zhu, C Guo - BMC neuroscience, 2021 - Springer
… At the same time, LPS injection in rat triggers cognitive impairment through activation of
NF-κB signaling pathway, and metformin administration alleviates the LPS-induced memory …

… cognitive impairment and ameliorates tau hyperphosphorylation by limiting the self-perpetuating pathogenic cycle between NF-κB signaling, oxidative stress and …

W He, C Wang, Y Chen, Y He, Z Cai - Pharmacological Reports, 2017 - Springer
… that it is via inhibiting the activation of NF-kB signaling pathway, and by … cognitive impairment
and limited tau hyperphosphorylation in an AD mice model (APP/PS1 transgenic mice). NF-…

Baicalin mitigates cognitive impairment and protects neurons from microglia‐mediated neuroinflammation via suppressing NLRP 3 inflammasomes and TLR 4/NFκB …

X Jin, MY Liu, DF Zhang, X Zhong, K Du… - CNS Neuroscience …, 2019 - Wiley Online Library
… This study aimed to investigate the effects of BAI pretreatment on cognitive impairment
and neuronal protection against microglia-induced neuroinflammation and to explore the …

Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments via the inhibition of NF-κB in male C57BL/6J mice and BV2 …

P He, S Yan, J Zheng, Y Gao, S Zhang… - Journal of agricultural …, 2018 - ACS Publications
… , amyloidogenesis, cognitive impairment, and the potential … the NF-κB and MAPK pathways.
These results indicated that eriodictyol alleviated amyloidogenesis and memory impairment

Supplementation of lycopene attenuates oxidative stress induced neuroinflammation and cognitive impairment via Nrf2/NF-κB transcriptional pathway

B Zhao, B Ren, R Guo, W Zhang, S Ma, Y Yao… - Food and Chemical …, 2017 - Elsevier
… CD-1 male mice cognitive impairments. LYC ameliorated … Nrf2 signaling and inactivation
of NF-κB translocation in a H 2 … and cognitive impairment possibly via mediating Nrf2/NF-κB

Altered KLOTHO and NF-κB-TNF-α signaling are correlated with nephrectomy-induced cognitive impairment in rats

S Degaspari, CB Tzanno-Martins, CK Fujihara, R Zatz… - PloS one, 2015 - journals.plos.org
… Renal insufficiency can have a negative impact on cognitive function. Neuroinflammation …
of cognitive impairment (CI). The present study evaluates the correlation of cognitive deficits …

NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration

T Ku, B Li, R Gao, Y Zhang, W Yan, X Ji, G Li… - Particle and fibre …, 2017 - Springer
… this action was mediated by NF-κB p65-induced downregulation of … and cognitive impairments
caused by PM 2.5 exposure. … for cognitive impairment and is largely reflected by impaired

[HTML][HTML] Electroacupuncture ameliorates cognitive impairment through inhibition of NF-κB-mediated neuronal cell apoptosis in cerebral ischemia-reperfusion injured …

X Feng, S Yang, J Liu… - Molecular …, 2013 - build.spandidos-publications.com
… genes of the NF-κB pathway. Collectively, our findings suggest that inhibition of NF-κB‑mediated …
at Baihui and Shenting exerts a therapeutic effect on post-stroke cognitive impairment. …

Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and NLRP3 inflammasome

P Liu, T Gao, T Li, Y Yang, Y Xu, Z Xu, W Mi - Neuroscience Letters, 2021 - Elsevier
… an effective inhibitor of NF-κB activation in many studies on cognitive dysfunction, diabetic …
of the NF-κB pathway and NLRP3 inflammasome in propofol-induced cognitive impairment. In …