… highly aggressive and common types of cancers, namely, colon and rectal. Globally, while
colon cancer is the fourth most common malignancy, rectum cancer is the eight most common …

… not only to define the molecular mechanisms underlying progression to … molecular targets
for therapy. In most tumours, several regulatory circuits are altered during multistage tumour …

… agent for the treatment of colorectal cancer. In this study, we investigate the molecular
mechanisms of … Exposure of colon cancer cells to oxaliplatin resulted in G2/M arrest and …

… are diagnosed with colorectal cancer, with a … cancer cell line models. Several in vivo and
in vitro studies have substantially proved their anticancer activities against colon cancer cell …

… HI colon cancer stem cells from cultured HCT 116 (wt-p53) cells … isolate colon cancer stem
cells from HCT 116 (wt-p53) cells (… markers for the isolation of colon cancer stem cells [48–51]. …

… of colon cancer. Inflammation is also likely to be involved with other forms of sporadic as
well as heritable colon cancer. The molecular mechanisms by which inflammation promotes …

… for combinatorial treatment. Further experimentation of the molecular mechanisms in RKO
colorectal cancer (CRC) cells revealed a p53-dependent induction of p21 and an increase in …

… Denbinobin suppressed colon cancer cell growth We first examined the antiproliferative
effect of denbinobin on the colon cancer cells. Treatment of the COLO 205 cells with 10 μmol/L …

… More recently, retinol treatment of colon cancer cells resulted in inhibition of cell migration
… catenin and inhibited cell invasion by suppressing PI3K activity in colon cancer cells 65, 66. …

… However, this review of the process of apoptosis is helpful in delineating important aspects
to provide insight into the recent status of this mechanism in the pathogenesis of colon cancer …