RET is a potential tumor suppressor gene in colorectal cancer

Y Luo, KD Tsuchiya, D Il Park, R Fausel, S Kanngurn… - Oncogene, 2013 - nature.com
… in colorectal cancer and (3) our finding of methylated RET in colorectal cancer suggest RET
could be a tumor suppressor … RET and methylated RET in colorectal cancer, we now provide …

Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome

S Sirnes, J Bruun, M Kolberg, A Kjenseth… - … journal of cancer, 2012 - Wiley Online Library
colorectal cancer tumor suppressor protein that predicts clinical outcome. Colorectal cancer
… The present study indicates that colorectal cancer patients with tumors that express Cx43 in …

Identifying tumor suppressor genes in human colorectal cancer

EJ Stanbridge - Science, 1990 - science.org
… The molecular identification of several candidate oncogene and tumor suppressor genes
in colorectal carcinoma is exciting and we eagerly await the cloning of the FAP gene on 5q. …

Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer

Y Kondo, LL Shen, JPJ Issa - Molecular and cellular biology, 2003 - Am Soc Microbiol
… maintenance of promoter DNA methylation-associated gene silencing in colorectal cancer.
… In cancer cells, hypermethylation of DNA in the promoter CpG islands of tumor suppressor

The co‐regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer

ML Slattery, JS Herrick, LE Mullany… - … and Cancer, 2017 - Wiley Online Library
Tumor suppressor genes (TSGs) and oncogenes (OG) are involved in carcinogenesis. … to
cellular pathways leading to cancer. We use data from 217 colorectal cancer (CRC) cases to …

Tumor suppressor functions of miR-133a in colorectal cancer

Y Dong, J Zhao, CW Wu, L Zhang, X Liu, W Kang… - Molecular Cancer …, 2013 - AACR
colorectal cancer tumors and … colorectal cancer specimens compared with matched adjacent
normal tissue. Ectopic expression of miR-133a significantly suppressed colorectal cancer

Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer

W Zhao, IM Hisamuddin, MO Nandan, BA Babbin… - Oncogene, 2004 - nature.com
… on chromosome 9q, previously shown to exhibit allelic loss in colorectal cancer (CRC). In this
study, we … These findings indicate that KLF4 is a potential tumor suppressor gene in CRC. …

GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer

DMEI Hellebrekers, MHFM Lentjes… - Clinical cancer …, 2009 - AACR
… are relevant tumor suppressor genes in colorectal cancer. … exhibit tumor suppressive
activities in colorectal cancer cells … specific in primary colorectal cancers. GATA4 methylation in …

[PDF][PDF] Tyrosine phosphatases as a superfamily of tumor suppressors in colorectal cancer

I Laczmanska, M Sasiadek - Acta Biochimica Polonica, 2011 - bibliotekanauki.pl
… of tyrosine kinases, are very important tumor suppressors. Alterations in tyrosine kinase and
… a variety of cancers. Colorectal cancer (CRC) is one of the most common cancers in humans…

Molecular biology of colorectal cancer

R Gryfe, B Bapat, S Gallinger, C Swallow… - … problems in cancer, 1997 - Elsevier
colorectal cancer (hereditary nonpolyposis colorectal cancer … Recent studies have examined
colorectal carcinogenesis in … in almost all cancers, including colorectal cancer, but rarely in …