Molecular analysis of blood vessel formation and disease

P Carmeliet, D Collen - American Journal of Physiology …, 1997 - journals.physiology.org
Blood vessels affect the quality of life in many ways. They … formation and pathobiology of blood
vessels. This review focuses on … With different murine models of cardiovascular disease, a …

Compromised blood–brain barrier integrity is associated with total magnetic resonance imaging burden of cerebral small vessel disease

Y Li, M Li, L Zuo, Q Shi, W Qin, L Yang, T Jiang… - Frontiers in …, 2018 - frontiersin.org
… studies have demonstrated that compromised blood–brain barrier (BBB) integrity may play
a pivotal role in the pathogenesis of individual cerebral small vessel disease (cSVD) markers, …

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success

G Dragneva, P Korpisalo… - Disease models & …, 2013 - journals.biologists.com
diseases (Folkman, 1971). The aim of angiogenic therapy in ischemic diseases is to stimulate
blood vessel growth in areas of poor vascularization in an attempt to increase blood supply…

Small vessel disease: mechanisms and clinical implications

JM Wardlaw, C Smith, M Dichgans - The Lancet Neurology, 2019 - thelancet.com
… When the layer of cells that line the blood vessels in the brain are not functioning properly,
which manifests in several ways. The cells lining the capillaries should regulate transport of …

Vascular cells in blood vessel wall development and disease

R Mazurek, JM Dave, RR Chandran, A Misra… - Advances in …, 2017 - Elsevier
blood vessel walls is intricately configured to meet the needs of the surrounding tissues.
Cardiovascular diseases … vascular wall may become compromised through diverse mechanisms…

Cerebrovascular and blood-brain barrier compromise: A mechanistic link between vascular disease and Alzheimer's disease subtypes of neurocognitive disorders

E Goldwaser, N Acharya, R Nagele - Journal of Parkinson's disease …, 2015 - rdw.rowan.edu
… BBB compromise. In most cases, these leak clouds were found surrounding or near the leaky
blood vessels (termed source blood vessels… extent and number of leaky blood vessels [18]. …

Angiogenesis and blood vessel stability in inflammatory arthritis

A Kennedy, CT Ng, M Biniecka, T Saber… - Arthritis & …, 2010 - Wiley Online Library
… result in increased release of ROS, coupled with a compromised antioxidant defense system
(22). Excessive … Correlation of ST blood vessel expression of NCAM with disease activity. …

Emerging evidence for pathogenesis of sporadic cerebral small vessel disease

M Ihara, Y Yamamoto - Stroke, 2016 - Am Heart Assoc
… fibers on the surface of damaged blood vessels and prevent platelet activation, thereby, …
immunoglobulins) and fluid through the compromised barrier of the penetrating arteries and …

How tumors make bad blood vessels and stroma

HF Dvorak - The American journal of pathology, 2003 - ASIP
… of inducing the formation of tumor-like blood vessels and connective tissue stroma. Further,
… immunity, and in chronic inflammatory diseases such as psoriasis and rheumatoid arthritis. …

[PDF][PDF] Lacunar infarction and small vessel disease: pathology and pathophysiology

LR Caplan - Journal of stroke, 2015 - synapse.koreamed.org
… walls of penetrating arteries compromise the continence of the vessels to components of
the … the blood-brain barrier by degrading tight junction proteins found within blood vessels.…