… original epigenetic clocks developed to predict chronological age. These new measures
show consistent evidence of more advanced and faster biological aging in people exposed to …

… and health span, the burgeoning field of epigenetics has shed light on the integrated nature
… methylation changes have been compared to an “epigenetic clock,” the time of which is set …

… DNAm probes used in common epigenetic clocks and immune cell proportion estimators
had varying distributions in each test-retest scenario. Notably, the robustness of the probes …

… that is not accounted for in computational cell-type deconvolution … epigenetic state we identify
is distinct from trained immunity. … Together, these observations suggest that the epigenetic …

… All targets are 100x100 multi-cellular arrays: the limited computational resources available
… -clock theory argues that ageing results from a preprogrammed sequence, as in a clock, built …

… epigenetic age (ImAge), a fundamentally different approach to studying aging compared to
DNAm clocks… the same coefficient 𝛼 i Such computations enabled us to identify key metabolic …

… clock is ±2.5 years (maximal correlation coefficient 0,98) (Horvath et al. 2018). Epigenetic
clocks … diploid human genome, coupled with computational algorithms, is sufficient to provide …

… across epigenetic clocks, we employed a PC-based approach to these epigenetic clocks
recently described by Higgens-Chen et al. as a way to increase reliability of epigenetic clock …

… evolution of the genetic programs within individuals and species, the ontogenetic level
concerns the developmental process of a single multicellular organism, and the epigenetic level …

… analyze their epigenetic data, at the same time conserving the accuracy in the epigenetic data
prediction. … Since the EPM model is computationally heavy, selecting informative loci in the …