[HTML][HTML] Recognition of variants of concern by antibodies and T cells induced by a SARS-CoV-2 inactivated vaccine

F Melo-González, JA Soto, LA González… - Frontiers in …, 2021 - frontiersin.org
… cells specific for SARS-CoV-2 Spike WT and variants of concern from vaccinated subjects …
antibodies able to block SARS-CoV-2 variants of concern and partially neutralizes SARS-CoV-…

[HTML][HTML] SARS-CoV-2 variants of concern

JY Choi, DM Smith - Yonsei medical journal, 2021 - ncbi.nlm.nih.gov
… Spike (S) protein of SARS-CoV-1, which had the ability to escape from neutralizing antibodies,
became the dominant variant as the outbreak proceeded. For SARS-CoV-2, the mutation …

[HTML][HTML] The spike of concern—the novel variants of SARS-CoV-2

A Winger, T Caspari - Viruses, 2021 - mdpi.com
… I converting enzyme 2) and many neutralising antibodies bind. While NTD mutations appear
… points enabling spike to escape neutralising antibodies while maintaining or even gaining …

[HTML][HTML] The emerging concern and interest SARS-CoV-2 variants

E Janik, M Niemcewicz, M Podogrocki, I Majsterek… - Pathogens, 2021 - mdpi.com
… The RBD is the major target of neutralizing antibodies (NAbs) induced by SARS-CoV-2
infection, with residual activity directed at the NTD [50]. Three of spike mutations are in the NTD (…

Immunity to SARS-CoV-2 variants of concern

DM Altmann, RJ Boyton, R Beale - Science, 2021 - science.org
… cell entry by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), were being …
eliciting neutralizing antibodies that block spike and therefore prevent the ability of SARS-CoV-…

[HTML][HTML] Immune response to SARS-CoV-2 variants of concern in vaccinated individuals

M Becker, A Dulovic, D Junker, N Ruetalo… - Nature …, 2021 - nature.com
… on the still controversial question of how efficiently antibodies can bind and neutralize
SARS-CoV-2 variants of concern. The presence of large titers of IgG antibodies within the saliva of …

[HTML][HTML] Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern

L Dupont, LB Snell, C Graham, J Seow, B Merrick… - Nature …, 2021 - nature.com
SARS-CoV-2 infection 7,8,9,10,11,12 , information on the durability and long-term cross-reactivity
of the antibody response against SARS-CoV-2 … the antibody response in SARS-CoV-2-…

[HTML][HTML] SARS-CoV-2 variants of concern are emerging in India

J Singh, SA Rahman, NZ Ehtesham, S Hira… - Nature medicine, 2021 - nature.com
… There was enrichment for the mutation T478K or T478R when SARS-CoV-2 was subjected
to weak neutralizing antibodies, which indicates this mutation may lead to antibody escape. …

[HTML][HTML] SARS-CoV-2 variants resistant to monoclonal antibodies in immunocompromised patients is a public health concern

A Casadevall, D Focosi - The Journal of clinical …, 2023 - Am Soc Clin Investig
Antibody-based antiviral therapies largely work by neutralizing virions. … of antibody-based
therapies, the mechanism of action of mAbs, and the mutation-prone nature of SARS-CoV-2. …

Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern

H Cho, KK Gonzales-Wartz, D Huang, M Yuan… - Science translational …, 2021 - science.org
antibodies and underscores the need for additional antibody-based … antibodies targeting
SARS-CoV-2 from plasmablasts and memory B cells collected from patients with coronavirus