… -binding and fusion core domains within the entire spike. Furthermore, our results show that
… that each spike can bind up to three ACE2 molecules. The SARS-CoV spike provides an …

… The coronavirus spike (S) glycoprotein initiates infection by promoting … conformational
changes that remain largely uncharacterized. Here we report the cryoEM structure of a coronavirus …

… ACE2 is a trigger for SARS-CoV spike to fuse membranes. … no or moderate conformational
changes of SARS-CoV spike … triggers a conformational change in SARS-CoV spike, which …

Full article: Computational analysis of protein stability and allosteric interaction networks in
distinct conformational forms of the SARS-CoV-2 spike D614G mutant: reconciling functional …

… Interestingly, the Spike protein … conformations. These simulations indicate that the steric
composition of the glycans can induce a pause during the Spike protein conformational change. …

… In this study, we report the structures of different conformational states of the SARS-CoV S
… These new data allow us to reorganize and optimize the current model for SARS-CoV entry (…

… also correlates with crucial conformation changes connected to (a) the … reorganization of
the S2. For (a), molecular dynamics simulations of the closed and open S protein conformations …

… To characterize the restructuring of the electric field of the S protein, we define the first four
moments of the non-dimensional charge distribution q ( x ) = sinh ( − ψ ( x ) ) in the solvent(27) …

… that use mRNA encoding a modified spike protein stabilized in its prefusion conformation. It
is … is to produce a spike protein stabilized in the prefusion conformation as a target to train the …

… COVID-19 will become an endemic disease requiring updated second-generation vaccines.
The SARS-CoV-2 surface spike (S… of S proteins associated with SARS-CoV-2, implemented …