… rats with AAV9 GFP and delineated the transduced regions in the brain and spinal cord. The
use … There was efficient and consistent transduction of motor neurons throughout the entire …

… Here we assessed the transduction of adult spinal cord at two different doses of AAV
vectors … preferable AAV9 serotype, Rec3 serotype transduced a broader region of the spinal …

… In this study, we compared transduction of spinal cord and cortex by AAV9… AAV9 into the
CM of NHPs was about 10-fold more efficient in transducing the brain than was vascular delivery…

… in the field of AAV gene delivery to the spinal cord, particularly … AAV serotypes and delivery
methodologies to the spinal cord. … for spinal cord transduction following systemic delivery in …

… Intrathecal delivery of AAV9 into the subarachnoid space has … In this study, we test transduction
of spinal cord by AAV-F (n = 3) … Here, we test transduction of spinal cord of AAV-F (n = 3) …

… Transduced spinal cord cells were fixed at 7 days post-transduction and processed for
immunocytochemistry using antibodies against neuronal tubulin marker MAP2 (a, c, e, g, i) and …

… transduction of MNs in the spinal cord of a large animal via intrathecal gene delivery using a
self-complementary AAV9. … translated to many MN diseases requiring diffuse gene delivery. …

… , while AAV 5 and 9 are the most suitable for lung transduction. … significant preference for
MNs in the spinal cord [83]. On the … astroglial transduction in the brain and spinal cord, only with …

… In this study, we describe the first successful study of whole spinal cord transduction after
systemic delivery of scAAV9 vectors in adult animals, including large animals like felines. High …

… also recently shown that AAV9 mediates transduction of the … of AAV9 mediated a far more
systemic transduction of epithelia… umbilical cord blood sampling) was used to administer AAV9 …