Eukaryotic core promoters and the functional basis of transcription initiation

V Haberle, A Stark - Nature reviews Molecular cell biology, 2018 - nature.com
functional diversity, which defines distinct transcription programmes. On the basis of the
established properties of gene core promotersfunctional assays to propose a functional model of …

Core promoters: active contributors to combinatorial gene regulation

ST Smale - Genes & development, 2001 - genesdev.cshlp.org
… that core promoter elements are functionally interchangeable in the context of simple,
synthetic … for a complete understanding of the mechanistic basis of core promoter preferences. …

Functional characterization of core promoter elements: the downstream core element is recognized by TAF1

DH Lee, N Gershenzon, M Gupta… - … and cellular biology, 2005 - Am Soc Microbiol
… In a similar vein, we moved S III in the Ad E3 promoter 3 base pairs closer or further from
its original position. In this case, the effects were equally deleterious, severely decreasing …

Core promoters in transcription: old problem, new insights

AL Roy, DS Singer - Trends in biochemical sciences, 2015 - cell.com
… can occupy over a hundred base pairs of DNA around the transcriptional start site (TSS) [ …
function of core promoters. In this review, we summarize the evidence that the core promoter

Regulatory enhancer–core-promoter communication via transcription factors and cofactors

MA Zabidi, A Stark - Trends in Genetics, 2016 - cell.com
… Through the combined activating or repressive cues of the different TFs and cofactors,
enhancers exert their overall regulatory function to control transcription from target core promoters

[HTML][HTML] The core promoter is a regulatory hub for developmental gene expression

A Sloutskin, H Shir-Shapira, RN Freiman… - Frontiers in Cell and …, 2021 - frontiersin.org
… In this mini-review, we will highlight the function of the core promoter as the regulatory
hub that recruits specific transcription factors to control key developmental gene expression …

Widespread enhancer activity from core promoters

A Medina-Rivera, D Santiago-Algarra, D Puthier… - Trends in biochemical …, 2018 - cell.com
… In vivo experiments demonstrated that enhancer like promoters function as bona fide … field
comes from the observation that many core promoter regions display enhancer activity. Recent …

The RNA polymerase II core promoter: a key component in the regulation of gene expression

JEF Butler, JT Kadonaga - Genes & development, 2002 - genesdev.cshlp.org
… individual core promoter elements, and then discuss the function of core promoter motifs in
… and important to understand the basis for the function of the BRE as a positive or negative …

[HTML][HTML] Links between core promoter and basic gene features influence gene expression

S Moshonov, R Elfakess, M Golan-Mashiach, H Sinvani… - BMC genomics, 2008 - Springer
function as found in yeast [2]. Table 2 Enrichment of functional categories of genes according
to core promoter … The mechanistic basis underlying the links between core promoter and …

Enhancer–promoter specificity mediated by DPE or TATA core promoter motifs

JEF Butler, JT Kadonaga - Genes & development, 2001 - genesdev.cshlp.org
… To investigate the basis for enhancer–promoter specificity, … vivo from core promoters containing
either downstream promoter … , the functional diversity of the core promoter increases the …