[HTML][HTML] Domains and functions of spike protein in Sars-Cov-2 in the context of vaccine design

X Xia - Viruses, 2021 - mdpi.com
… Almost all vaccine candidates against SARS-CoV-2 are based on the spike protein, … /BioNTech
and Moderna vaccines that use mRNA encoding a modified spike protein stabilized in its …

Vaccine design for severe acute respiratory syndrome coronavirus

Y He, S Jiang - Viral immunology, 2005 - liebertpub.com
vaccines designed against feline CoVs predispose some cats to accelerated disease and
death. For instance, the S protein of … of disease if the vaccinated animals are subsequently …

[PDF][PDF] Drug and vaccine design against Novel Coronavirus (2019-nCoV) spike protein through Computational approach

S Kumar - 2020 - pdfs.semanticscholar.org
… In this study using spike protein of noval coronavirus predicted B-cell and T-cell epitopes
for vaccine development. The epitopes predicted by using IEDB webserver using parameters …

… and immunogenic characterization of recombinant baculovirus-expressed severe acute respiratory syndrome coronavirus spike protein: implication for vaccine design

Y He, J Li, S Heck, S Lustigman, S Jiang - Journal of virology, 2006 - Am Soc Microbiol
… immunogenicity of recombinant baculovirus-expressed S proteins have been finely
characterized. Our findings have significant impact for designing a safe and effective SARS vaccine. …

Protective immunity against SARS subunit vaccine candidates based on spike protein: lessons for coronavirus vaccine development

A Khalaj-Hedayati - Journal of immunology research, 2020 - Wiley Online Library
… In general, coronavirus spike protein is the major antigen for the vaccine design as it can
induce … immunity needs to be considered in the aim of coronavirus universal vaccine design. …

[HTML][HTML] COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning

E Ong, MU Wong, A Huffman, Y He - Frontiers in immunology, 2020 - frontiersin.org
… of the multi-domain nsp3 protein, which was predicted to have … structural S protein and
non-structural proteins (including … vaccine strategy for rational COVID-19 vaccine development. …

Design of an epitope-based peptide vaccine against spike protein of human coronavirus: an in silico approach

AR Oany, AA Emran, TP Jyoti - … design, development and therapy, 2014 - Taylor & Francis
… based vaccine designed for HCoV. In this study, a computational approach was adopted to
identify a multiepitope vaccine … Sequences of the spike proteins were collected from a protein

Vaccine development against coronavirus (2003 to present): An overview, recent advances, current scenario, opportunities and challenges

KC Badgujar, VC Badgujar, SB Badgujar - Diabetes & Metabolic Syndrome …, 2020 - Elsevier
coronavirus vaccine designing may play crucial role in development of rapid vaccine against
COVID-19… is the most widely used protein segment in coronavirus vaccine design due to its …

[HTML][HTML] In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms

S Cankat, MU Demael, L Swadling - Cellular & molecular immunology, 2024 - nature.com
… effective antiviral immunity to coronaviruses and have informed next-generation vaccine
design. We will then consider the ideal properties of a pan-coronavirus vaccine and propose a …

Multiepitope Subunit Vaccine Design against COVID‐19 Based on the Spike Protein of SARS‐CoV‐2: An In Silico Analysis

HA Dar, Y Waheed, MH Najmi, S Ismail… - Journal of …, 2020 - Wiley Online Library
vaccines [21, 22]. In this study, we used a computer-assisted vaccine design approach against
COVID-… were done on the spike protein of novel coronavirus species to select promising T-…