… Although the current RPA appears to accurately stratify patients in the temozolomide era, 4
the original classes were not identified using a training set of temozolomide-treated patients …

… Further, statistically significant improvement over time was only observed in patients who
received radiation, which is expected to correlate with temozolomide use in the 2005–2008 …

… and current clinical application of temozolomide, which, until … that determine sensitivity to
temozolomide. More reliable … we make a case for revisiting temozolomide use in a broader …

… evaluated in the current temozolomide (TMZ) era. The aim of this meta-analysis was to pool
the … significance of reoperation EOR for glioblastoma recurrence in the current TMZ era. …

Purpose Temozolomide (TEM) based therapy has been reported being effective in the treatment
of metastatic neuroendocrine neoplasms (NEN), with response rates ranging from 30 to …

… cohorts did not considerably affect our analysis. The focus of this study was to conduct a
comparative analysis of prediction models in the era of temozolomide CCRT (ie, by analyzing …

… In 1999, the US Food and Drug Administration approved the alkylating agent temozolomide
(… same Cox model, the HRs did not take into account correlation among treatment modalities. …

… (RT) and temozolomide (TMZ) in an open-label, phase II study (NCI-06-C-0112). The intent
of the current study was to compare our patient outcomes with modern era standard of care …

… methylation may predict benefit from alkylating agents such as temozolomide. The aim of
our study was to evaluate the activity of temozolomide in terms of response rate in patients with …

… Our study found a correlation between PTEN loss and EGFR amplification. It has been … the
PI3k/Akt pathway could hold independent or correlative prognostic significance. For example, …