cotH Genes Are Necessary for Normal Spore Formation and Virulence in Mucor lusitanicus

C Szebenyi, Y Gu, T Gebremariam, S Kocsubé… - MBio, 2023 - Am Soc Microbiol
Mucormycosis is an invasive fungal infection caused by certain members of the fungal order
of Mucorales. The species most frequently identified as the etiological agents of
mucormycosis belong to the genera Rhizopus, Lichtheimia, and Mucor. The frequency of
systemic mucormycosis has been increasing, mainly because of increasing numbers of
susceptible patients. Furthermore, Mucorales display intrinsic resistance to the majority of
routinely used antifungal agents (eg, echinocandins and short-tailed azoles), which limits …

CotHgenes are necessary for normal spore formation and virulence inMucor lusitanicus

C Szebenyi, Y Gu, T Gebremariam, S Kocsubé… - 2022 - europepmc.org
Mucormycosis is an invasive fungal infection caused by certain members of the fungal order
of Mucorales. The species most frequently identified as the etiological agents of
mucormycosis belong to the genera Rhizopus, Lichtheimia and Mucor. The frequency of
systemic mucormycosis has been increasing, mainly because of the elevating numbers of
susceptible patients. Furthermore, Mucorales display intrinsic resistance to the majority of
routinely used antifungal agents (eg, echinocandins and short-tailed azoles), which limits …
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