REGEN-COV antibody combination and outcomes in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
… COV, a combination of the monoclonal antibodiescoronavirus disease 2019 (Covid-19).
REGEN-COV has activity in vitro against current severe acute respiratory syndrome coronavirus

Subcutaneous REGEN-COV antibody combination to prevent Covid-19

MP O'Brien, E Forleo-Neto, BJ Musser… - … England Journal of …, 2021 - Mass Medical Soc
… from complications of Covid-19. When we initiated the REGEN-COV program, we hypothesized
that a combination of neutralizing, noncompeting monoclonal antibodies could have …

Antibody response of combination of BNT162b2 and CoronaVac platforms of COVID-19 vaccines against Omicron variant

KW Khong, D Liu, KY Leung, L Lu, HY Lam, L Chen… - Vaccines, 2022 - mdpi.com
… already received two doses of COVID-19 vaccines, we aimed to … combination of vaccinations:
two doses of BNT162b2 followed by one dose of BNT162b2 booster (BBB); Combination of …

[HTML][HTML] Neutralizing monoclonal antibodies for treatment of COVID-19

PC Taylor, AC Adams, MM Hufford… - Nature Reviews …, 2021 - nature.com
… and the potential benefit of combining antibodies to defend against emerging viral variants.
… from mild COVID-19 demonstrated neutralizing antibody and S-binding antibody titres that …

Neutralizing antibody therapeutics for COVID-19

AC Hurt, AK Wheatley - Viruses, 2021 - mdpi.com
… -2 neutralizing antibodies (nAbs) in the clinical management of COVID-19 and provide an …
evaluating the combination of bamlanivimab with etesevimab in ambulatory COVID-19 patients…

Effect of subcutaneous casirivimab and imdevimab antibody combination vs placebo on development of symptomatic COVID-19 in early asymptomatic SARS-CoV-2 …

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - Jama, 2022 - jamanetwork.com
… contact, treatment with subcutaneous casirivimab and imdevimab antibody combination
vs placebo significantly reduced the incidence of symptomatic COVID-19 over 28 days. …

Virologic efficacy of casirivimab and imdevimab COVID-19 antibody combination in outpatients with SARS-CoV-2 infection: a phase 2 dose-ranging randomized …

C Portal-Celhay, E Forleo-Neto, W Eagan… - JAMA Network …, 2022 - jamanetwork.com
… et al; COVID-19 Phase 3 Prevention Trial Team. Effect of subcutaneous casirivimab and
imdevimab antibody combination vs placebo on development of symptomatic COVID-19 in early …

COVID-19 antibody therapeutics tracker: a global online database of antibody therapeutics for the prevention and treatment of COVID-19

L Yang, W Liu, X Yu, M Wu, JM Reichert… - Antibody …, 2020 - academic.oup.com
… A combination (cocktail) of two antibodies that recognize different non-competing epitopes
of the RBD or the spike protein of SARS-CoV-2 has been developed for clinical trials to …

Phase 2 dose-ranging study of the virologic efficacy and safety of the combination COVID-19 antibodies casirivimab and imdevimab in the outpatient setting

C Portal-Celhay, E Forleo-Neto, W Eagan, BJ Musser… - medRxiv, 2021 - medrxiv.org
… in coronavirus disease 2019 (COVID-19) outpatients (NCT04425629) found that the
REGEN-COV ® antibody combination, … for antibodies against severe acute respiratory syndrome …

REGN-COV2, a neutralizing antibody cocktail, in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
… The full analysis set included the first 275 patients with Covid-19 symptoms who underwent
randomization in the combined phase 1–2 portions of the trial. A sample of 275 patients (72 …