COVID-19: antiviral agents, antibody development and traditional Chinese medicine

W Guan, W Lan, J Zhang, S Zhao, J Ou, X Wu, Y Yan… - Virologica Sinica, 2020 - Springer
COVID-19 outbreak are urgently needed. To facilitate the better and faster development
of therapeutic COVID-19 … drugs, including repurposing existing antiviral agents, network-based …

Antiviral agent therapy optimization in special populations of COVID-19 patients

L Li, X Wang, R Wang, Y Hu, S Jiang… - … design, development and …, 2020 - Taylor & Francis
… Some potential drugs have shown antiviral effects on SARS-CoV-2 infections, such as … in
COVID-19 patients of these antiviral agents and provided the potential antiviral agent options …

Antiviral treatment of COVID-19

S Yavuz, S Ünal - Turkish journal of medical sciences, 2020 - journals.tubitak.gov.tr
… 6-fluoro-3-hydroxy-2pyrazinecarboxamide) is an antiviral agent that selectively and potently
inhibits the RNA-dependent RNA polymerase (RdRp) of RNA viruses. Favipiravir undergoes …

Antiviral agents for the treatment of COVID-19: Progress and challenges

M Singh, E de Wit - Cell Reports Medicine, 2022 - cell.com
Antiviral therapies have greatly improved the clinical outcome in COVID-19 patients, especially
… Here, we discuss the successes and challenges of COVID-19 antiviral therapies and …

Favipiravir, an antiviral for COVID-19?

EA Coomes, H Haghbayan - Journal of Antimicrobial …, 2020 - academic.oup.com
… As the scale of the ongoing COVID-19 outbreak has reached … COVID-19 remain to be
defined, significant interest exists in repurposing existing antiviral agents for use against COVID-19

Small-molecule antiviral agents in ongoing clinical trials for COVID-19

ÇB Apaydın, G Çınar, G Cihan-Üstündağ - Current drug targets, 2021 - ingentaconnect.com
… Most of the antiviral discovery efforts are focused on the repurposing of approved or clinical
antiviral agents that are currently under investigation in clinical trials for COVID-19. These …

Plausible mechanisms of Niclosamide as an antiviral agent against COVID-19

SKSS Pindiprolu, SH Pindiprolu - Medical hypotheses, 2020 - Elsevier
… Recently, it was also reported that, NIC exhibited in vitro antiviral activity … for COVID-19. The
plausible therapeutic mechanisms by which NIC acts as an antiviral agent against COVID-19

Developing a direct acting, orally available antiviral agent in a pandemic: the evolution of molnupiravir as a potential treatment for COVID-19

GR Painter, MG Natchus, O Cohen, W Holman… - Current opinion in …, 2021 - Elsevier
antiviral agent originally designed for the treatment of Alphavirus infections, into a potential
drug for the prevention and treatment of COVID-19. … As COVID-19 spread, the timeline for the …

Clinical effectiveness of oral antiviral agents in older patients with COVID19 based on real‐world data

YW Tsai, JY Wu, TH Liu, MH Chuang… - Journal of medical …, 2023 - Wiley Online Library
… safe antiviral agent in older patients with COVID-19 aged ≥80 years, 29 this study did not
assess the safety of novel oral antiviral agents in the treatment of older people with COVID-19. …

Carbon-based nanomaterials: promising antiviral agents to combat COVID-19 in the microbial-resistant era

Á Serrano-Aroca, K Takayama, A Tuñón-Molina… - ACS …, 2021 - ACS Publications
… for the COVID-19 disease. This Review addresses the application of these broad-spectrum
CBNs as antimicrobial agents by analyzing a large number of antiviral … to treat COVID-19. …