Use of antiviral drugs to reduce COVID-19 transmission

O Mitjà, B Clotet - The Lancet Global Health, 2020 - thelancet.com
… acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2… The current COVID-19
emergency warrants the urgent … —even if more robust data on antiviral therapies is yet to come. A …

Repurposed antiviral drugs for Covid-19—interim WHO solidarity trial results

WHO Solidarity Trial Consortium - New England journal of …, 2021 - Mass Medical Soc
… We randomly assigned inpatients with Covid-19 equally between one of the trial drug … trial
drug and its control (drug available but patient assigned to the same care without that drug). …

A brief review of antiviral drugs evaluated in registered clinical trials for COVID-19

D Belhadi, N Peiffer-Smadja, FX Lescure… - MedRxiv, 2020 - medrxiv.org
COVID-19, we conducted a review of registered clinical trials. … coronavirus”. We included
interventional clinical trials focusing on patients with COVID-19 and assessing antiviral drugs or …

Antiviral treatment of COVID-19

S Yavuz, S Ünal - Turkish journal of medical sciences, 2020 - journals.tubitak.gov.tr
… start antiviral treatment as soon as possible also for COVID-19 … Combined usage of antiviral
drugs for COVID-19 patients … case; adverse drug reactions and drug-drug interactions should …

[HTML][HTML] Antivirals for COVID-19: a critical review

A Frediansyah, R Tiwari, K Sharun, K Dhama… - … and global health, 2021 - Elsevier
COVID-19 cases in some countries. Since clinical trials to assess the efficacy of available
antivirals for COVID-19 … This review summarizes antiviral drugs that can be potentially used for …

Efficacy of repurposed antiviral drugs: lessons from COVID-19

MA Martinez - Drug Discovery Today, 2022 - Elsevier
… New antiviral drugs targeting different SARS-CoV-2 … drugs on COVID-19. Experience with
previous virus pandemics has shown us that developing an ample repertoire of antiviral drugs

Antiviral drug discovery for the treatment of COVID-19 infections

TI Ng, I Correia, J Seagal, DA DeGoey, MR Schrimpf… - Viruses, 2022 - mdpi.com
… coverage to combat the current COVID-19 crisis as well as emerging coronaviruses with …
the discovery of antiviral drugs for COVID-19, covering the functions of important antiviral targets …

Current strategies of antiviral drug discovery for COVID-19

M Mei, X Tan - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
… by the US FDA for treating COVID-19. However, remdesivir’s … antiviral drugs are still urgently
needed. We will discuss the current status of the drug discovery efforts against COVID-19

Clinical trials with antiviral drugs against COVID19: some progress and many shattered hopes

H Brüssow - Environmental Microbiology, 2021 - Wiley Online Library
… unprepared drugantiviral drugs against COVID-19 and explore in the second part reasons
for the frequent negative outcome of these drug trials and the challenges facing antiviral drug

Accelerating antiviral drug discovery: lessons from COVID-19

A von Delft, MD Hall, AD Kwong, LA Purcell… - Nature Reviews Drug …, 2023 - nature.com
… sector organizations that have substantial research and development efforts in COVID-19.
We outline key lessons from rapid antiviral drug discovery efforts, or ‘sprints’, and articulate …