Current perspective of antiviral strategies against COVID-19

BA Ahidjo, MWC Loe, YL Ng, CK Mok… - ACS infectious …, 2020 - ACS Publications
… Since the discovery of COVID-19 in December 2019, numerous antiviralsantiviral strategies
currently employed and summarizes reported in vitro and in vivo efficacies of key antiviral

Novel antiviral strategies in the treatment of COVID-19: a review

SJ Chen, SC Wang, YC Chen - Microorganisms, 2020 - mdpi.com
… as a novel antiviral strategy for the treatment of COVID-19. … licensed vaccine products for
COVID-19. Under the condition … and efficacy for COVID-19 treatment, novel antiviral strategies, …

Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
… So far, a few small-molecule antiviral … of COVID-19, mostly requiring administration within
10 days of symptom onset. In addition, hospitalized patients with severe or critical COVID-19

Use of antiviral drugs to reduce COVID-19 transmission

O Mitjà, B Clotet - The Lancet Global Health, 2020 - thelancet.com
… The current COVID-19 emergency warrants the urgent development of potential strategies
… , among others—even if more robust data on antiviral therapies is yet to come. A key reason …

Current strategies of antiviral drug discovery for COVID-19

M Mei, X Tan - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
… treating COVID-19. However, remdesivir’s clinical effects are controversial and new antiviral
drugs … We will discuss the current status of the drug discovery efforts against COVID-19 and …

Update on antiviral strategies against COVID-19: unmet needs and prospects

CH Liu, CH Lu, SH Wong, LT Lin - Frontiers in Immunology, 2021 - frontiersin.org
COVID-19 management, including the virus-targeting inhibitors and host-targeting agents,
with their antiviral … future prospect of developing potent therapeutic agents against COVID-19. …

Antiviral therapy for COVID-19: Derivation of optimal strategy based on past antiviral and favipiravir experiences

K Shiraki, N Sato, K Sakai, S Matsumoto… - Pharmacology & …, 2022 - Elsevier
… in treating refractory CMV pneumonia, COVID-19 pneumonia should be prevented with …
antiviral therapy for COVID-19 based on clinical trials of favipiravir for the treatment of COVID-19

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
… the pathogenesis of COVID-19. Both the virus and host factors are potential targets for
antiviral therapy. Hence, in this study, the current therapeutic strategies of COVID-19 have been …

Comparing antiviral strategies against COVID-19 via multiscale within-host modelling

F Fatehi, RJ Bingham, EC Dykeman… - Royal Society …, 2021 - royalsocietypublishing.org
antiviral therapy and assess their synergies. We focus here on two prominent forms of therapy
against COVID-19… that remdesivir is an effective antiviral treatment option for COVID-19 [4]. …

Science-based strategies of antiviral coatings with viricidal properties for the COVID-19 like pandemics

R Pemmada, X Zhu, M Dash, Y Zhou, S Ramakrishna… - Materials, 2020 - mdpi.com
… highly-innovative antiviral agents to work against the viruses. We hypothesize that some of
the antiviral coatings discussed here could exert an inhibitive effect on COVID-19, indicated …