Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential

E Gorman, J Millar, D McAuley… - Expert review of …, 2021 - Taylor & Francis
… therapy in ARDS and sepsis is discussed. The potential for MSC therapy in COVID-19 ARDS
is … of MSC therapy in COVID-19. Strategies to optimize the therapeutic potential of MSCs in …

COVID-19 and Sepsis

ZK Tufan, B Kayaaslan, M Mer - Turkish journal of medical …, 2021 - journals.tubitak.gov.tr
… respiratory failure, heart disease and impaired immune status are at enhanced risk of more
severe COVID-19, including ARDS, multiorgan failure, and death [39,44]. This severe form of …

Steroids for sepsis and ARDS: this eternal controversy remains with COVID-19

J Carlet, D Payen, SM Opal - The Lancet, 2020 - thelancet.com
COVID-19 In the past 50 years, the potential benefit of corticosteroids in treating sepsis or
acute respiratory distress syndrome (ARDS) … were efficacious for ARDS of various origin. This …

Innate receptor activation patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel …

R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
… occur in severe COVID-19, influenza-associated ALI/ARDS and sepsis and also differentiate
COVID-19 and influenza virus or bacterial infections that do not lead to ALI/ARDS or sepsis. …

Bioinformatics and system biology approach to identify the influences among COVID-19, ARDS and sepsis

P Li, T Li, Z Zhang, X Dai, B Zeng, Z Li, Z Li - Frontiers in Immunology, 2023 - frontiersin.org
… To analyze shared genetic interrelations and potential therapeutic targets among COVID-19,
ARDS and sepsis, we obtained both microarray and RNA-seq datasets from the Gene …

[HTML][HTML] Cytokine profile in plasma of severe COVID-19 does not differ from ARDS and sepsis

JG Wilson, LJ Simpson, AM Ferreira, A Rustagi… - JCI insight, 2020 - ncbi.nlm.nih.gov
ARDS and sepsis (9). If the inflammatory response in severe COVID-19 is no different than
that in ARDS or sepsis, testing of immune modulators in unselected COVID-19 patients may …

How sepsis parallels and differs from COVID-19

A Herminghaus, MF Osuchowski - EBioMedicine, 2022 - thelancet.com
COVID-19 patients (78%) met the Sepsis 3.0 criteria for sepsis/septic shock with acute respiratory
distress syndrome … Conversely, COVID-19 ARDS features a robust alveolar thrombosis …

Multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS

R Batra, W Whalen, S Alvarez-Mulett… - PLoS …, 2022 - journals.plos.org
… In our study, 158 TAGs and 29 DAGs had higher levels in COVID-19 ARDS compared to
bacterial sepsis-induced ARDS while 102 TAGs and 3 DAGs had lower levels. …

[HTML][HTML] Characteristics and outcomes of sepsis patients with and without COVID-19

L Heubner, S Hattenhauer, A Güldner… - Journal of Infection and …, 2022 - Elsevier
… with sepsis and 177 patients with sepsis and COVID-19 were enrolled in this study. These
177 sepsis patients with COVID-19 … Mortality in COVID-19 caused ARDS patients seems to be …

A hub gene signature as a therapeutic target and biomarker for sepsis and geriatric sepsis-induced ARDS concomitant with COVID-19 infection

G Qian, H Fang, A Chen, Z Sun, M Huang… - Frontiers in …, 2023 - frontiersin.org
… as biomarkers for predicting COVID-19 and sepsis-induced ARDS, we employed a murine
model of sepsis-induced ARDS as a proxy for both COVID-19 and sepsis-related lung injuries…