Natural killer cell dysfunction and its role in COVID-19

C van Eeden, L Khan, MS Osman… - International journal of …, 2020 - mdpi.com
… There are many parallels between infection, genetics and physiology and NK cell dysregulation.
In this section we share aspects of NK cell dysfunction that are not related to infections …

COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… patients with severe COVID-19, leading to lymphopenia, lymphocyte dysfunction, and …
dysfunction. Therefore, mechanisms underlying immune abnormalities in patients with COVID-19

Endothelial cell dysfunction, coagulation, and angiogenesis in coronavirus disease 2019 (COVID-19)

AH Norooznezhad, K Mansouri - Microvascular research, 2021 - Elsevier
… cytokine storm in which endothelial cell (EC) dysfunction is one of them. In COVID-19,
two main pathologic phenomena have been seen as a result of EC dysfunction: hyper-coagulation …

Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19

F Karagiannis, K Peukert, L Surace, M Michla… - Nature, 2022 - nature.com
… To gain insight into the metabolic features of T cells in COVID-19 ARDS, we used
SCENITH to analyse a subgroup of patients with COVID-19. T cells in the BALF and blood of …

NK cell dysfunction in patients with COVID-19

J Bi - Cellular & molecular immunology, 2022 - nature.com
… by COVID-19-associated NK cells. In addition, NK cells from patients with severe COVID-19
displayed a similar gene expression signature to pulmonary NK cells from patients with lung …

COVID-19, renin-angiotensin system and endothelial dysfunction

R Amraei, N Rahimi - Cells, 2020 - mdpi.com
cell injury could exacerbate endothelial dysfunction, which is … dysfunction and injury offers
insights into COVID-19 … endothelial dysfunction and SARS-CoV-2 induced endothelial injury in …

Endothelial dysfunction in Covid-19 infection

HM Otifi, BK Adiga - The American journal of the medical sciences, 2022 - Elsevier
cells (ECs) in critical COVID-19 and its further understanding might be of therapeutic implications.
Severe COVID-19 is … In severe COVID 19, endothelial dysfunction involves not only pro …

Endothelial dysfunction in COVID-19: lessons learned from coronaviruses

E Gavriilaki, P Anyfanti, M Gavriilaki, A Lazaridis… - Current hypertension …, 2020 - Springer
… of severe coronavirus disease-2019 (COVID-19) infection resemble the clinical phenotype of
endothelial dysfunction … Importantly, endothelial dysfunction has been suggested as a main …

Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
… contribution of endothelial dysfunction to COVID-19 and its sequelae, we overviewed, in this
article, the pivotal role and mechanistic basis of endothelial dysfunction in COVID-19 and its …

Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection with severe
acute respiratory syndrome coronavirus … ARDS) and other organ dysfunctions. Therapeutic …