… with fatal COVID-19, providing an atlas of lung immunopathology of the disease. We found a broad tropism of SARS-CoV-2 infection in pulmonary parenchymal and immune cells. …
SR da Silva, E Ju, W Meng, AEP Mondolfi, S Dacic… - medRxiv, 2020 - medrxiv.org
… with fatal COVID-19, providing an atlas of lung immunopathology of the disease. We found a broad tropism of SARS-CoV-2 infection in pulmonary parenchymal and immune cells. …
… Although COVID-19 is principally thought of as a pulmonary disease, increasing evidence … tissue tropism (16) and that dysfunction of multiple organs occurs in COVID-19 (17). The …
E Wauters, K Thevissen, C Wouters… - Frontiers in …, 2020 - frontiersin.org
… Successful COVID-19 patient management and therapeutic … -CoV2-tropism and COVID-19-immunopathology into a single … immune-dysregulation during COVID-19. In particular, we …
JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
… immune system in the immunopathology of COVID-19. Indeed, the … response in patients with COVID-19; in particular, we … drives the hyperinflammatory syndrome in severe COVID-19. …
LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
… changes observed in COVID‐19 within the most commonly affected organ systems, with special emphasis on immunopathology. Current management strategies for COVID‐19 include …
DWL Wong, BM Klinkhammer, S Djudjaj, S Villwock… - Cells, 2021 - mdpi.com
… methods allowing tissue and cellular localization in autopsies. We provide a “cellular and whole-body tissue atlas” of organ tropism profile of SARS-CoV-2 in severe COVID-19 patients, …
J Wang, Q Li, YW Qiu, H Lu - Emerging Microbes & Infections, 2022 - Taylor & Francis
… It is also demonstrated that SARS-CoV-2 widespread tropism for nasal epithelial cell types, resulting in the type I and III IFNs response in the nasal airway. The interferon response is …
B Schurink, E Roos, T Radonic, E Barbe… - The Lancet …, 2020 - thelancet.com
… In 11 patients tested for SARS-CoV-2 tropism, SARS-CoV-2 infected cells were present in multiple organs, most abundantly in the lungs, but presence in the lungs became sporadic with …