Broad severe acute respiratory syndrome coronavirus 2 cell tropism and immunopathology in lung tissues from fatal coronavirus disease 2019

S Ramos da Silva, E Ju, W Meng… - The Journal of …, 2021 - academic.oup.com
… with fatal COVID-19, providing an atlas of lung immunopathology of the disease. We found
a broad tropism of SARS-CoV-2 infection in pulmonary parenchymal and immune cells. …

[PDF][PDF] Broad SARS-CoV-2 cell tropism and immunopathology in lung tissues from fatal COVID-19

SR Da Silva, E Ju, W Meng, AE Paniz Mondolfi… - J. Infect. Di, 2021 - scholar.archive.org
… with fatal COVID-19, providing an atlas of lung immunopathology of the disease. We found
a broad tropism of SARS-CoV-2 infection in pulmonary parenchymal and immune cells. …

Broad SARS-CoV-2 cell tropism and immunopathology in lung tissues from fatal COVID-19

SR da Silva, E Ju, W Meng, AEP Mondolfi, S Dacic… - medRxiv, 2020 - medrxiv.org
… with fatal COVID-19, providing an atlas of lung immunopathology of the disease. We found
a broad tropism of SARS-CoV-2 infection in pulmonary parenchymal and immune cells. …

Tissue-specific immunopathology in fatal COVID-19

DA Dorward, CD Russell, IH Um, M Elshani… - American journal of …, 2021 - atsjournals.org
… Although COVID-19 is principally thought of as a pulmonary disease, increasing evidence
… tissue tropism (16) and that dysfunction of multiple organs occurs in COVID-19 (17). The …

Establishing a unified COVID-19 “immunome”: integrating coronavirus pathogenesis and host immunopathology

E Wauters, K Thevissen, C Wouters… - Frontiers in …, 2020 - frontiersin.org
… Successful COVID-19 patient management and therapeutic … -CoV2-tropism and COVID-19-immunopathology
into a single … immune-dysregulation during COVID-19. In particular, we …

[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19

JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
… immune system in the immunopathology of COVID-19. Indeed, the … response in patients
with COVID-19; in particular, we … drives the hyperinflammatory syndrome in severe COVID-19. …

COVID19: immunopathology, pathophysiological mechanisms, and treatment options

LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
… changes observed in COVID19 within the most commonly affected organ systems, with
special emphasis on immunopathology. Current management strategies for COVID19 include …

Multisystemic cellular tropism of SARS-CoV-2 in autopsies of COVID-19 patients

DWL Wong, BM Klinkhammer, S Djudjaj, S Villwock… - Cells, 2021 - mdpi.com
… methods allowing tissue and cellular localization in autopsies. We provide a “cellular and
whole-body tissue atlas” of organ tropism profile of SARS-CoV-2 in severe COVID-19 patients, …

COVID-19: imbalanced cell-mediated immune response drives to immunopathology

J Wang, Q Li, YW Qiu, H Lu - Emerging Microbes & Infections, 2022 - Taylor & Francis
… It is also demonstrated that SARS-CoV-2 widespread tropism for nasal epithelial cell types,
resulting in the type I and III IFNs response in the nasal airway. The interferon response is …

[HTML][HTML] Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study

B Schurink, E Roos, T Radonic, E Barbe… - The Lancet …, 2020 - thelancet.com
… In 11 patients tested for SARS-CoV-2 tropism, SARS-CoV-2 infected cells were present in
multiple organs, most abundantly in the lungs, but presence in the lungs became sporadic with …