… The SARS-CoV-2 virus primarily binds to type-2 pneumocyte cells in the alveoli of the
lungs which further invades into cell surfaces of specific receptors like hACE2 and CD90L [43]. …

… lung puncture taken from the dead body of severe COVID-19 … the whole lungs of surgical
critical patient of COVID-19, … of immunologic cells were present focally in lung interstitium and …

… These results consistently support our finding that COVID-19 infection also enhanced its
expression in lung epithelial cells. Another study showed anti-ICAM1 antibody could inhibit …

… a lung organoid model using human pluripotent stem cells (hPSCs) that could be adapted
for drug screens. The lung organoids, particularly aveolar type II cells, … human COVID-19 …

… , but might be less relevant when studying severe COVID-19, where infection of alveolar cells
or inflammation in the distal lung can lead to potentially fatal ARDS (Ackermann et al., 2020…

… is a cell-surface protein widely existed on cells in the heart, … , especially lung alveolar
epithelium type 2 cells. Considering … cells and the cytokine storm and could be used in COVID-19 …

… lung pathologies and facilitates respiratory infections. Apparently, a relationship between
life-threatening COVID-19 lung … into the lungs could aggravate age-related senescent cell …

… and CD34 in endothelia of pulmonary vessels using COVID-19 lung tissues (upper panel,
Case 1) or control lung tissues from a patient with lung carcinoma (lower panel). Scale bars, …

… Using this approach, we integrated > 300,000 single-cell transcriptomic profiles from
COVID-19-affected lungs and tissues from healthy subjects and patients with five inflammatory …

… The loss of type II alveolar epithelial cells in COVID-19 leads to loss of surfactant
regulation and production [80]. Although due to limited studies on the early pathogenesis of …