D Murata, K Azuma, S Tokisawa, T Tokito… - Thoracic …, 2022 - Wiley Online Library
… (CRS) is a systemic inflammatory disease … by COVID-19 infection during treatment with nivolumab and ipilimumab. Fever is a common event in cancer patients, especially in COVID-19-…
… patients with COVID-19 presenting cytokinereleasesyndrome, thus … IL-6 blockade is considered a therapeutic target to control cytokinereleasesyndrome (CRS) related to COVID-19…
D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… subgroup of patients with severe COVID-19 might have a cytokinereleasesyndrome. Such patients have high levels of pro-inflammatory cytokines and chemokines that are associated …
DE Leisman, L Ronner, R Pinotti, MD Taylor… - The Lancet …, 2020 - thelancet.com
… in patients with cytokinereleasesyndrome was 575 pg/mL; the difference between mean IL-8 concentration in patients with cytokinereleasesyndrome versus COVID-19 was not …
… cytokinereleasesyndrome (CRS) and mortality in patients with acute severe respiratory syndromecoronavirus 2 (… the severity of coronavirusdisease 2019 (COVID-19) via endogenous …
P Chen, Y Tang, W He, R Yang, Z Lan… - Mediators of …, 2022 - Wiley Online Library
… cytokine interaction network and identify that four cytokines play … “cytokine” to summarize the cytokines and pathways involved in CRS-related organ damage. Finally, we took “COVID-19…
JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
… This cytokinereleasesyndrome (CRS) may occur in up to 70% of patients depending on conditioning therapy and cell construct, with ICU admission rates up to 13% [[36], [37], [38]]. …
… in COVID-19 including compromised immunity, worsening coagulopathy, and depletion of blood bank resources [18]. The cytokinereleasesyndrome is … 20% of COVID-19 cases [19]. …
L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… Moreover, tocilizumab has been shown to be effective against cytokinereleasesyndrome resulting from CAR-T cell infusion against B cell acute lymphoblastic leukemia. Blocking anti-…