[HTML][HTML] COVID-19-induced cytokine release syndrome associated with pulmonary vein thromboses, atrial cardiomyopathy, and arterial intima inflammation

A Goette, M Patscheke, F Henschke… - TH Open, 2020 - thieme-connect.com
… levels of inflammatory cytokines might be involved in the development of organ dysfunction
in COVID-19. Here, we can present a case of cytokine release syndrome induced by SARS–…

A case of cytokine release syndrome accompanied with COVID19 infection during treatment with immune checkpoint inhibitors for non‐small cell lung cancer

D Murata, K Azuma, S Tokisawa, T Tokito… - Thoracic …, 2022 - Wiley Online Library
… (CRS) is a systemic inflammatory disease … by COVID-19 infection during treatment with
nivolumab and ipilimumab. Fever is a common event in cancer patients, especially in COVID-19-…

Efficacy and safety of early treatment with sarilumab in hospitalised adults with COVID-19 presenting cytokine release syndrome (SARICOR STUDY): protocol of a …

RL López, SC Fernández, LL Pérez, AR Palacios… - BMJ open, 2020 - bmjopen.bmj.com
… patients with COVID-19 presenting cytokine release syndrome, thus … IL-6 blockade is
considered a therapeutic target to control cytokine release syndrome (CRS) related to COVID-19

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… subgroup of patients with severe COVID-19 might have a cytokine release syndrome. Such
patients have high levels of pro-inflammatory cytokines and chemokines that are associated …

[HTML][HTML] Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes

DE Leisman, L Ronner, R Pinotti, MD Taylor… - The Lancet …, 2020 - thelancet.com
… in patients with cytokine release syndrome was 575 pg/mL; the difference between mean
IL-8 concentration in patients with cytokine release syndrome versus COVID-19 was not …

Interleukin-1 Receptor Antagonist Gene (IL1RN) Variants Modulate the Cytokine Release Syndrome and Mortality of COVID-19

M Attur, C Petrilli, S Adhikari, E Iturrate… - The Journal of …, 2024 - academic.oup.com
cytokine release syndrome (CRS) and mortality in patients with acute severe respiratory
syndrome coronavirus 2 (… the severity of coronavirus disease 2019 (COVID-19) via endogenous …

Potential pathophysiological mechanisms underlying multiple organ dysfunction in cytokine release syndrome

P Chen, Y Tang, W He, R Yang, Z Lan… - Mediators of …, 2022 - Wiley Online Library
cytokine interaction network and identify that four cytokines play … “cytokine” to summarize
the cytokines and pathways involved in CRS-related organ damage. Finally, we took “COVID-19

Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
… This cytokine release syndrome (CRS) may occur in up to 70% of patients depending on
conditioning therapy and cell construct, with ICU admission rates up to 13% [[36], [37], [38]]. …

[HTML][HTML] Efficacy of therapeutic plasma exchange in the treatment of penn class 3 and 4 cytokine release syndrome complicating COVID-19

WL Gluck, SP Callahan, RA Brevetta, AE Stenbit… - Respiratory …, 2020 - Elsevier
… in COVID-19 including compromised immunity, worsening coagulopathy, and depletion
of blood bank resources [18]. The cytokine release syndrome is … 20% of COVID-19 cases [19]. …

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… Moreover, tocilizumab has been shown to be effective against cytokine release syndrome
resulting from CAR-T cell infusion against B cell acute lymphoblastic leukemia. Blocking anti-…