Tocilizumab: a therapeutic option for the treatment of cytokine storm syndrome in COVID-19

A Saha, AR Sharma, M Bhattacharya, G Sharma… - Archives of medical …, 2020 - Elsevier
… for this COVID-19 outbreak. … disease is associated with a high level of release of cytokine
in the patients which is known as CRS (cytokine release syndrome) or cytokine storm syndrome

IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome

S Kang, T Tanaka, H Inoue, C Ono… - Proceedings of the …, 2020 - National Acad Sciences
… Consistent with previous reports, the serum IL-6 concentrations in the severe COVID-19
patients examined in this study were relatively lower than those in patients with severe ARDS (29…

[HTML][HTML] Tocilizumab in a child with acute lymphoblastic leukaemia and COVID-19-related cytokine release syndrome

PV Puyó, L Moreno, CD de Heredia, JG Rivière… - Anales de …, 2020 - ncbi.nlm.nih.gov
… Due to suspicion of cytokine release syndrome (CRS), described elsewhere as a predictor …
levels of C-reactive protein (CRP), interleukin-6 (IL-6) and ferritin (Fig. 1 ), and the patient was …

Spotlight on tocilizumab in the treatment of CAR-T-cell-induced cytokine release syndrome: clinical evidence to date

S Si, DT Teachey - Therapeutics and clinical risk management, 2020 - Taylor & Francis
… The current coronavirus disease 2019 (COVID-19) pandemic has inflicted a devastatingly
high morbidity and mortality rate across the globe. Citation69,Citation70 Although we are only …

COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue

X Yongzhi - Emerging microbes & infections, 2021 - Taylor & Francis
… (MAS), infection-associated hemophagocytic syndrome, cytokine release syndrome (CRS),
and cytokine storm (CS). Hematologic malignancies and autoimmune diseases that cause …

[HTML][HTML] HIV and Associated indicators of COVID-19 cytokine release syndrome: a Meta-analysis and Meta-regression

JK Muthuka Jr, K Oluoch, FM Wambura, JM Nzioki… - Cureus, 2023 - ncbi.nlm.nih.gov
… The aim of this review was to evaluate the risk of COVID-19 cytokine release syndrome (CRS)
with HIV infection and meta-regress for indicator covariates. Electronic databases, …

[HTML][HTML] Effectiveness of tocilizumab in a COVID-19 patient with cytokine release syndrome

S Uslu - European journal of case reports in internal medicine, 2020 - ncbi.nlm.nih.gov
… We describe a case of CRS caused by severe COVID-19 infection with a favourable … -6
(IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (…

Mast cell's role in cytokine release syndrome and related manifestations of COVID-19 disease

Ö Özdemir, AY Göksu Erol… - Current Pharmaceutical …, 2022 - ingentaconnect.com
… ' role in cytokine release syndrome and related manifestations of COVID-19 disease were
reviewed by … Recommendations for the management of cytokine release syndrome and related …

[HTML][HTML] Laboratory parameters predicting mortality of adult in-patients with COVID-19 associated cytokine release syndrome treated with high-dose tocilizumab

B Lakatos, BG Szabo, I Bobek, L Gopcsa… - Acta Microbiologica et …, 2021 - akjournals.com
… tocilizumab for critically ill COVID-19 patients requiring organ … IL-6 blockade with tocilizumab
may be demonstrated in the presence of COVID-19 associated cytokine release syndrome

Tocilizumab treatment for cytokine release syndrome in hospitalized patients with coronavirus disease 2019.

CC Price, FL Altice, Y Shyr, A Koff, L Pischel, G Goshua… - 2020 - cabidigitallibrary.org
release syndrome (CRS), with observed improvements in a coronavirus disease 2019 (COVID-19) …
with COVID-19. Study Design and Methods: This observational study of consecutive …