How COVID-19 induces cytokine storm with high mortality

S Hojyo, M Uchida, K Tanaka, R Hasebe… - Inflammation and …, 2020 - Springer
… that IL-6-STAT3 signaling is a promising therapeutic target for the cytokine storm in COVID-19,
because IL-6 … mechanism and potential therapeutic targets of ARDS in COVID-19 patients. …

The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
cytokine storm and the options to inhibit the cytokine storm, in … for the clinical diagnosis and
treatment of COVID-19. … type coronavirus infection causes an inflammatory cytokine storm

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… between cytokine storm and severe COVID-19 complications, we propose a cytokine
storm-based diagnosis and management workflow for patients with or suspected of COVID-19 (…

When does the cytokine storm begin in COVID-19 patients? A quick score to recognize it

S Cappanera, M Palumbo, SH Kwan, G Priante… - Journal of clinical …, 2021 - mdpi.com
coronavirus disease 2019 (COVID-19), which has rapidly spread across the world, becoming
a pandemic. The “cytokine storm” (CS) in COVID-19 … , and cytokine antagonists may be the …

COVID-19 cytokine storm: targeting the appropriate cytokine

RQ Cron - The Lancet Rheumatology, 2021 - thelancet.com
… in improving COVID-19IL-6 inhibition in the treatment of COVID-19 cytokine storm syn
drome. 7 This single-centre, observational study of patients admitted to hospital with COVID-19, …

A glimpse into the eye of the COVID-19 cytokine storm

K Kuppalli, AL Rasmussen - EBioMedicine, 2020 - thelancet.com
… interpretations of COVID-19-specific effects on inflammatory cytokine production and immune
… with cytokine storms and COVID-19 severity, further data from other cohorts of COVID-19

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… The purpose of this study was to determine whether critically ill COVID-19 patients have an
exaggerated proinflammatory cytokine storm versus an immunosuppressive immunological …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… decrease the outbreak of COVID-19 and mitigate its symptoms [… COVID-19 may be a promising
intervention for COVID-19-… understanding of cytokines-induced alterations in COVID-19, …

T cell immunobiology and cytokine storm of COVID19

XH Luo, Y Zhu, J Mao, RC Du - Scandinavian journal of …, 2021 - Wiley Online Library
… SARS is an instance of cytokine storms that give rise to a robust … Similarly, cytokine storm is
a critical profile of patients with COVID-19 … of IL-6. Higher plasma concentrations of IL-2, IL2R, …

On the alert for cytokine storm: immunopathology in COVID19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
… Absent the opportunity to enroll patients in one of these studies, we would consider
immunosuppression in patients with COVID-19 who have incipient cytokine storm. Ideally, treatment …