Utilizing drug repurposing against COVID-19efficacy, limitations, and challenges

V Parvathaneni, V Gupta - Life sciences, 2020 - Elsevier
… discovery of new therapies against COVID-19. In this article, … regarding efficacy of repurposed
drugs against COVID-19 and … COVID-19 epidemiology, and then have discussed drug

Efficacy of repurposed antiviral drugs: lessons from COVID-19

MA Martinez - Drug Discovery Today, 2022 - Elsevier
… of these newly developed drugs on COVID-19. Experience with previous virus pandemics
has shown us that developing an ample repertoire of antiviral drugs with different targets will …

Systematic review on the therapeutic options for COVID-19: clinical evidence of drug efficacy and implications

AR Abubakar, IH Sani, B Godman… - Infection and drug …, 2020 - Taylor & Francis
… mortality in patients with severe COVID-19. In addition, convalescent plasma … COVID-19.
There is currently no single worldwide approved therapeutic option for patients with COVID-19

Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

HM Dabbous, S Abd-Elsalam, MH El-Sayed… - Archives of …, 2021 - Springer
drugs have been approved for the treatment of COVID-19. This study aimed to evaluate the
efficacy of favipiravir in treatment of COVID-19. … promising drug for treatment of COVID-19 that …

Efficacy of Remdesivir in COVID-19

EK McCreary, DC Angus - Jama, 2020 - jamanetwork.com
… The experimental antiviral drug remdesivir (manufactured by Gilead) was granted … US Food
and Drug Administration in May 2020 for patients hospitalized with severe COVID-19. At the …

Understanding COVID-19 vaccine efficacy

M Lipsitch, NE Dean - Science, 2020 - science.org
… of the COVID-19 outbreak, several drugsCOVID-19 vaccine will decree the death of the
drugs repurposing era? It seems unlikely. Drug repurposing is the evaluation of existing drugs

Metabolomics to predict antiviral drug efficacy in COVID-19

M Migaud, S Gandotra, HS Chand… - American Journal of …, 2020 - atsjournals.org
… In the United States, the most promising drug therapy thus far has been remdesivir (GS-…
and Drug Administration to allow emergency use access of the drug for COVID-19 treatment on …

Addressing COVID19 drug development with artificial intelligence

D Ho - Advanced Intelligent Systems, 2020 - Wiley Online Library
efficacy in treating COVID-19. However, its emergence has also led to a large number of
clinical trials evaluating drug … to move beyond traditional drug screening and repurposing by …

[HTML][HTML] Clinical efficacy of antivirals against novel coronavirus (COVID-19): A review

S Jomah, SMB Asdaq, MJ Al-Yamani - Journal of infection and public health, 2020 - Elsevier
… In recent past, out of the all drug therapies explored for combating COVID-19, antivirals
exhibited promising results. Some of them are tested due to their earlier beneficial role against …

A review of potential suggested drugs for coronavirus disease (COVID-19) treatment

P Tarighi, S Eftekhari, M Chizari, M Sabernavaei… - European Journal of …, 2021 - Elsevier
COVID-19; most of them are undergoing clinical trials. This article summarizes clinical
investigations of potential therapeutic drugs used as COVID-19 … , covid-19 antiviral drugs' efficacy