Molnupiravir: A new candidate for COVID19 treatment

F Pourkarim, S Pourtaghi‐Anvarian… - Pharmacology …, 2022 - Wiley Online Library
… Several studies have investigated the inhibitory effects of molnupiravir on COVID-19 replication
… in the future to confirm the therapeutic effects of molnupiravir in patients with COVID-19. …

Molnupiravir in COVID-19: A systematic review of literature

AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2021 - Elsevier
… Finally, cost effectiveness and accessibility for all is a major issue that needs to be dealt
with and effect of molnupiravir with other therapies for COVID-19 needs to be examined. The …

Molnupiravir, an oral antiviral treatment for COVID-19

W Fischer, JJ Eron Jr, W Holman, MS Cohen, L Fang… - MedRxiv, 2021 - medrxiv.org
… However, a Phase 2/3 study is ongoing to evaluate the effect of molnupiravir on symptom
duration and severity, emergency department visits, and hospitalizations (ClinicalTrials.gov …

Effect of molnupiravir on biomarkers, respiratory interventions, and medical services in COVID-19: a randomized, placebo-controlled trial

MG Johnson, A Puenpatom, PA Moncada… - Annals of internal …, 2022 - acpjournals.org
… of molnupiravir for the treatment of mild to moderate COVID-19 … and COVID-19–related
acute care visits were evaluated in all randomly assigned participants who received molnupiravir

Antiviral efficacy of molnupiravir for COVID-19 treatment

Y Bai, M Shen, L Zhang - Viruses, 2022 - mdpi.com
… the placebo and Molnupiravir groups, and a random effect, … infected individual receives the
Molnupiravir treatment on day … of COVID-19 is 5 and all infected people take the Molnupiravir

Molnupiravir and its antiviral activity against COVID-19

L Tian, Z Pang, M Li, F Lou, X An, S Zhu… - Frontiers in …, 2022 - frontiersin.org
… trials, molnupiravir showed beneficial effects for … molnupiravir are also summarized and
discussed, aiming to expand our knowledge on molnupiravir and better deal with the COVID-19

[HTML][HTML] Efficacy and safety of molnupiravir for COVID-19 patients

M Fatima, S Azeem, J Saeed, A Shahid… - European Journal of …, 2022 - ncbi.nlm.nih.gov
… The therapeutic effect of molnupiravir can be described based on its 2-step mutagenesis
mechanism. In the first step, RdRp uses positive-strand genomic RNA +gRNA to synthesize a …

[HTML][HTML] The pill of recovery; Molnupiravir for treatment of COVID-19 patients; a systematic review

L Kamal, A Ramadan, S Farraj, L Bahig… - Saudi Pharmaceutical …, 2022 - Elsevier
… In this study, the treatment effect estimates for the primary end point, which was the rate
of hospitalization or death through day 29, was reduced in the all-randomized analysis as …

Randomized trial of molnupiravir or placebo in patients hospitalized with Covid-19

JR Arribas, S Bhagani, SM Lobo, I Khaertynova… - NEJM …, 2022 - evidence.nejm.org
… To evaluate molnupiravir’s effect on viral RNA error rates, nasopharyngeal samples
containing >22,000 copies/ml of SARS-CoV-2 RNA underwent complete genome next-generation …

Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … England Journal of …, 2022 - Mass Medical Soc
… of treatment with molnupiravir started … Covid-19 and at least one risk factor for severe
Covid-19 illness. Participants in the trial were randomly assigned to receive 800 mg of molnupiravir