Efficacy and safety of sofosbuvir in the treatment of SARS-CoV-2: an open label phase II trial

M Alavi-Moghaddam, M Sistanizad… - Frontiers in …, 2022 - publish.kne-publishing.com
… RdRp of the COVID-19 RNA (17,18), here we report the preliminary results of the randomized,
controlled, phase II open-label clinical trial of the safety and efficacy of sofosbuvir among …

Clinical efficacy and safety of antiviral drugs in the extended use against COVID-19: what we know so Far

MJ Hossain, T Jannat, SR Brishty, U Roy, S Mitra… - Biologics, 2021 - mdpi.com
… clinical trial (ChiCTR2000029387) on patients with mild to moderate severity of COVID-19
divided into three groups (ribavirin (RBV) + Ia: LPV/RTV + IFN-a: ribavirin + LPV/r + IFN-a = 1:1…

Efficacy and safety of umifenovir for coronavirus disease 2019 (COVID19): A systematic review and meta‐analysis

D Huang, H Yu, T Wang, H Yang… - Journal of medical …, 2021 - Wiley Online Library
… urgently in COVID-19 patients, such as interferon, ribavirin, hydroxychloroquine, lopinavir
and ritonavir, umifenovir, and so on. However, the specific effectiveness of these drugs for …

Evaluation of the effect of sofosbuvir and daclatasvir in hospitalised COVID-19 patients: a randomized double-blind clinical trial (DISCOVER)

S Mobarak, M Salasi, A Hormati, J Khodadadi, M Ziaee… - 2021 - papers.ssrn.com
… preliminary efficacy for patients with COVID-19 in five … sofosbuvir and daclatasvir to standard
care improved clinical endpoints in hospitalized patients with moderate or severe COVID-19

Spotlight of remdesivir in comparison with ribavirin, favipiravir, oseltamivir and umifenovir in coronavirus disease 2019 (COVID-19) pandemic

S Vafaei, M Razmi, M Mansoori… - … in Coronavirus …, 2019 - papers.ssrn.com
efficacy against this global challenge. A systematic literature review was performed to screen
all of the related papers on COVID-19… safety and efficacy of remdesivir, ribavirin, favipiravir, …

Efficacy and safety of antiviral treatment for COVID-19 from evidence in studies of SARS-CoV-2 and other acute viral infections: a systematic review and meta-analysis

W Liu, P Zhou, K Chen, Z Ye, F Liu, X Li, N He, Z Wu… - Cmaj, 2020 - Can Med Assoc
COVID-19. We found no direct evidence for treatment using ribavirin in a population of patients
with COVID-19, … no support for a reduction in mortality with ribavirin treatment.22 , 29 , 30 …

Novel coronavirus treatment with ribavirin: groundwork for an evaluation concerning COVID19

JS Khalili, H Zhu, NSA Mak, Y Yan… - Journal of medical …, 2020 - Wiley Online Library
… of ribavirin efficacy from 2003 during SARS and the 2013 MERS outbreaks led to a summary
evaluation of its utility as controversial in the treatment of COVID-19 … of ribavirin efficacy in a …

Safety and efficacy of antiviral combination therapy in symptomatic patients of Covid-19 infection-a randomised controlled trial (SEV-COVID Trial): a structured …

PK Panda, A Bandyopadhyay, BC Singh… - Trials, 2020 - Springer
efficacy of Hydroxychloroquine with Ribavirin and standard treatment in patients with non-severe
COVID-19 … Symptomatic (severe or non-severe) Covid-19 disease 4. Willingness of …

Anti-HCV, nucleotide inhibitors, repurposing against COVID-19

AA Elfiky - Life sciences, 2020 - Elsevier
… The present study presents a perfect model for COVID-19 … IDX-184, Sofosbuvir, and Ribavirin
against COVID-19 RdRp are … that IDX-184, Sofosbuvir, and Ribavirin can tightly bind to the …

Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

HM Dabbous, S Abd-Elsalam, MH El-Sayed… - Archives of …, 2021 - Springer
… Other antiviral drugs have been suggested to be repurposed for the treatment of COVID-19,
such as interferon-ɑ, lopinavir/ritonavir, ribavirin, and remdesivir [5, 6]. Some clinical trials …