Mechanistic and therapeutic implications of extracellular vesicles as a potential link between Covid-19 and cardiovascular disease manifestations

G Pironti, DC Andersson, LH Lund - Frontiers in Cell and …, 2021 - frontiersin.org
… In this scenario EVs might be linked to cardiovascular manifestations of the Covid-19 disease
… of Covid-19 and highlight potential strategies to control the extracellular signaling for future …

The significance of phenotyping and quantification of plasma extracellular vesicles levels using high-sensitivity flow cytometry during COVID-19 treatment

I Kudryavtsev, O Kalinina, V Bezrukikh, O Melnik… - Viruses, 2021 - mdpi.com
… participation of extracellular vesicles (EVs) in the pathogenesis of coronavirus infection, its
… with SARS-CoV-2 dissemination via vesicles and cell-origination markers, characterizing …

Update on extracellular vesicle-based vaccines and therapeutics to combat COVID-19

T Mustajab, MS Kwamboka, DA Choi, DW Kang… - International Journal of …, 2022 - mdpi.com
… for the development of vaccines against COVID-19. Along with the … coronavirus or controlling
the cytokine storm, we also discuss the obstacles to the clinical use of extracellular vesicles

Activated platelets and platelet-derived extracellular vesicles mediate COVID-19-associated immunothrombosis

M Ebeyer-Masotta, T Eichhorn, R Weiss… - Frontiers in Cell and …, 2022 - frontiersin.org
coronavirus disease-19 (COVID-19) caused by the severe acute respiratory syndrome
coronavirus … platelet-derived extracellular vesicles (pEVs) in COVID-19-related immunothrombosis…

Extracellular vesicles: versatile nanomediators, potential biomarkers and therapeutic agents in atherosclerosis and COVID-19-related thrombosis

A Georgescu, M Simionescu - International journal of molecular sciences, 2021 - mdpi.com
… A high rate of thrombotic events occurs in coronavirus disease-2019 (COVID-19) … coronavirus-2
(SARS-CoV-2). Here, we will discuss novel data regarding the role of EVs in COVID-19-…

Extracellular vesicles in COVID-19 convalescence can regulate T cell metabolism and function

MS George, J Sanchez, C Rollings, D Fear, P Irving… - Iscience, 2023 - cell.com
… be implicated in producing long-covid symptoms. Here, we assess the role of extracellular
vesicles (EV) in regulating T cell function over several weeks post COVID-19 disease. We find …

Decoy ACE2-expressing extracellular vesicles that competitively bind SARS-CoV-2 as a possible COVID-19 therapy

JM Inal - Clinical Science, 2020 - portlandpress.com
… of coronavirus that appeared in 2019, SARS-CoV-2, is the causative agent of severe respiratory
disease, COVID-19, … be to use ACE2 + -small extracellular vesicles (sEVs). A competitive …

Extracellular vesicles in COVID-19 prognosis, treatment, and vaccination: An update

A Hernández-Díazcouder, C Díaz-Godínez… - Applied Microbiology …, 2023 - Springer
… The lethality of the COVID 19 pandemic became the trigger … On the other hand, considering
that COVID 19 is here to stay, … of the benefits offered by extracellular vesicles (EVs), …

Persistent circulation of soluble and extracellular vesicle‐linked Spike protein in individuals with postacute sequelae of COVID19

V Craddock, A Mahajan, L Spikes… - Journal of medical …, 2023 - Wiley Online Library
… as new or persistent symptoms of COVID-19 beyond 4 weeks of acute … and post-acute
COVID-19 disease pathogenesis, identify … extracellular vesicles (EVs) from hospitalized COVID-19

Small extracellular vesicles and COVID19—using the “trojan horse” to tackle the giant

BM Borowiec, A Angelova Volponi, P Mozdziak… - Cells, 2021 - mdpi.com
… the relapse of the COVID-19 infection. Extracellular vesicles containing Covid-19 may be
a possible mechanism for the reappearance of the viral RNA in the recovered COVID-19