… For a better mechanistic understanding of COVID-19, our present review focuses on its …
activation of hypoxia inducible factor 1α (HIF-1α) and cell entry of SARS-CoV-2, since HIF-1α is …

… So, in this study the possible effect of the HIF-1α on the COVID-19 pathogenesis with … which
induces HIF-1α transcriptional activity [66]. In severe cases of COVID-19, HIF-1α activation …

… involving HIF-1α inhibitors or HIF-1α switchers to HIF-2α to guard against the generation
of cytokine storms and by default against COVID-19's systemic and pulmonary complications. …

… Given that the relationship observed between IL-1β, IL-6, and IL-10 in inflamed COVID ICU
patients was consistent with increased HIF-mediated transcription, we searched for evidence …

… data, we suggest that HIF-1 stabilization by HIF-1 stabilizers, a novel … COVID-19 infection
by a variety of mechanisms. Firstly, during COVID-19 infection, there may be upregulation of HIF…

… for COVID-19 control. Here, we identify that SARS-CoV-2 ORF3a and host hypoxia-inducible
factor-1α (HIF-1α) … RNA sequencing shows that HIF-1α signaling, immune response, and …

… deterioration of COVID-19 are discussed as a function of the upregulated expression of the
hypoxia-inducible factor-1 (HIF-1) and of the metabolic reprogramming associated with HIF-1 …

… Both HIF-1α and P2X7 receptors are linked to epileptogenesis and seizures. Therefore, in …
that COVID-19 may have a role in epileptogenesis and seizure through HIF-1α stimulation and …

… COVID-19 pandemia is a major health emergency causing … , HIF-1α, and ABL tyrosine
kinases. This review also highlights potential targets for prevention and therapy of COVID-19-…

… and HIF-1α levels and … HIF-1α in blood monocytes isolated from critical COVID-19 patients.
Codo et al. further identified that HIF-1α inhibition or stabilization blocks or exacerbates HIF-…