JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
… Disease severity in COVID-19 appears to be modulated not just by viral infection but also by aberrant immune and inflammatory responses in the host. Recent data suggest that this …
L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… and showed reduced viral replication and aberrant host inflammatory response. In addition, dihydroorotate dehydrogenase (DHODH) inhibitors were shown to be effective in infected …
… response of SARS-CoV-2 with other respiratory viruses to identify transcriptional signatures that may underlie COVID-19 … Despite virus replication, the hostresponse to SARS-CoV-2 …
… host’s pulmonary immune response and its contributions to disease severity and systemic inflammation. Comparing to frontline COVID-19 … of the hostresponse using biomaterials and …
D Tripathi, M Sodani, PK Gupta, S Kulkarni - Current research in …, 2021 - Elsevier
… Dexamethasone: Enhanced proinflammatory response is associated with the severity of COVID-19 disease; therefore, use of anti-inflammatory drugs at the right time might be helpful in …
… To understand the cytokine profile in BALF from the COVID-19 patients, we assigned DEGs into … These observations suggested that the exuberant inflammation in COVID-19 could be …
A Tufan, AA Güler… - Turkish journal of medical …, 2020 - journals.tubitak.gov.tr
… be considered as treatment choices for COVID-19, particularly in severe … COVID-19, we have focused the attention on the structural features of SARS-CoV-2, the host immune response …
… in COVID-19 by targeting the hostresponse to the virus has been made. However, their use needs to be deepened, since ACE inhibitors and angiotensin II-receptor blockers have been …
K Yuki, M Fujiogi, S Koutsogiannaki - Clinical immunology, 2020 - Elsevier
… immune response to COVID-19 … host receptors (attachment), they enter host cells through endocytosis or membrane fusion (penetration). Once viral contents are released inside the host …