Aging‐related cell type‐specific pathophysiologic immune responses that exacerbate disease severity in aged COVID19 patients

Y Hou, Y Zhou, L Jehi, Y Luo, MU Gack, TA Chan… - Aging …, 2022 - Wiley Online Library
… This study provides a comprehensive analysis of immune profiles in aged and younger
COVID-19 patients using large, electronic patient data from the CDC and the Cleveland Clinic …

Pathophysiology and mechanism of long COVID: a comprehensive review

D Castanares-Zapatero, P Chalon, L Kohn… - Annals of …, 2022 - Taylor & Francis
… possible pathophysiological mechanisms underlying lingering symptoms after COVID-19. …
Indeed, a weaker immune response could certainly play a role in long COVID [Citation114], …

Pathophysiology of SARS-CoV-2: targeting of endothelial cells renders a complex disease with thrombotic microangiopathy and aberrant immune response. The …

C Bryce, Z Grimes, E Pujadas, S Ahuja, MB Beasley… - MedRxiv, 2020 - medrxiv.org
… Mount Sinai Hospital on 67 COVID-19 positive patients and data … RESULTS Laboratory
results of our COVID-19 cohort show … autopsy series of 67 COVID-19 positive patients revealing …

COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment

A Parasher - Postgraduate medical journal, 2021 - academic.oup.com
… Both chloroquine and HCQS have been observed to have immunomodulatory effects and
have the capacity to suppress the massive immune response in COVID-19 (cytokine storm) …

Immune response in COVID-19: what is next?

Q Li, Y Wang, Q Sun, J Knopf, M Herrmann… - Cell Death & …, 2022 - nature.com
… Because of their central role in the pathophysiology of COVID-19, NET is a prime target
for therapeutical intervention. Therapeutic doses of heparin were shown to prevent the …

Pathophysiology and clinical management of coronavirus disease (COVID-19): a mini-review

Y Zhu, L Sharma, D Chang - Frontiers in Immunology, 2023 - frontiersin.org
… insights into the pathophysiology of COVID-19 and available … COVID-19 incidence,
hospitalization, mortality, and long … of COVID-19 involves a wide range of antiviral and immune

Post-COVID-19 syndrome

JD Pierce, Q Shen, SA Cintron, JB Hiebert - Nursing research, 2022 - journals.lww.com
… variations that affect many mechanisms but specifically oxidative stress, immune function, …
We also discuss the known pathophysiological changes that occur in post-COVID-19

EULAR points to consider on pathophysiology and use of immunomodulatory therapies in COVID-19

A Alunno, A Najm, PM Machado… - Annals of the …, 2021 - ard.bmj.com
pathophysiological mechanisms, including immune abnormalities, play a key role in COVID-19.
… to consider (PtCs) on COVID-19 pathophysiology and immunomodulatory therapies from …

Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments

SJ Yong - Infectious diseases, 2021 - Taylor & Francis
… induce some level of immune activation contributing to long COVID. A review has proposed
that T-cells dysfunction may promote long COVID pathophysiology similarly in autoimmune …

Understanding the pathophysiology of COVID-19: could the contact system be the key?

S Meini, A Zanichelli, R Sbrojavacca, F Iuri… - Frontiers in …, 2020 - frontiersin.org
… The Role of the Contact System in the Pathophysiology of COVID-19 The Contact System
(CS) is part of the innate immune system and of inflammatory response mechanism against …