COVID-19, immune system response, hyperinflammation and repurposingantirheumatic drugs

A Tufan, AA Güler… - Turkish journal of medical …, 2020 - journals.tubitak.gov.tr
immune response against SARS-CoV-2 may be considered fundamental for the resolution
of COVID-19. … Eventually, the exact pathophysiologic mechanism of COVID-19 remains still …

… from pathophysiology: Use of individualized combination treatments with immune interventional agents to tackle severe respiratory failure in patients with COVID-19

GN Dalekos, A Stefos, S Georgiadou, V Lygoura… - European Journal of …, 2021 - Elsevier
… in the Infectious Disease Unit of the Department of Internal Medicine at the General University
Hospital of Larissa, Greece, which is the referral center for the management of COVID-19

COVID-19 and immunothrombosis: Pathophysiology and therapeutic implications

MS Lim, S Mcrae - Critical Reviews in Oncology/Hematology, 2021 - Elsevier
… , although immunothrombosis, an interplay between the immune system and the coagulation
… discuss the pathophysiology, clinical, laboratory and therapeutic implications of COVID-19

[HTML][HTML] Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
… In conclusion, notwithstanding possible brain infiltration, the indirect CNS immune-mediated
damage seems to be the primary pathogenic mechanism of neuropsychiatric …

[HTML][HTML] Inflammasomes: a rising star on the horizon of COVID-19 pathophysiology

M Wang, F Yu, W Chang, Y Zhang, L Zhang… - Frontiers in …, 2023 - frontiersin.org
… Melatonin may represent an attractive supplemental treatment to alleviate immune over-activation
and the cytokine storm in COVID-19 patients. Continued research efforts are needed …

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
… infection of the lung and lung pathophysiology in critical COVID-19. In addition, we discuss
… exhibit profound immune exhaustion in patients with critical COVID-19, accompanied by a …

The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
… We review the intricacies of COVID-19 pathophysiologyCOVID-19 and respiratory failure
of other origins, but evidence for many distinctive mechanistic features indicates that COVID-19

[HTML][HTML] A review of pathophysiology and neuropsychiatric manifestations of COVID-19

M Jasti, K Nalleballe, V Dandu, S Onteddu - Journal of neurology, 2021 - Springer
… The postulated common pathophysiologic mechanisms include dysregulation of
cytokines/chemokines, deficiencies in the innate immune response, direct infection of immune cells, …

Immune responses during COVID-19 infection

C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
… The unpredictability of coronavirus disease-19 (COVID-19) poses a major burden on health
care … and cognate immune responses underlying protective or deleterious immune reactions …

COVID-19: Immunology and treatment options

S Felsenstein, JA Herbert, PS McNamara… - Clinical …, 2020 - Elsevier
coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions. As protective
immunity … and clinical features of COVID-19, pathophysiological mechanisms, and already …