A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?

B Shakaib, T Zohra, A Ikram, MB Shakaib, A Ali… - Virology journal, 2021 - Springer
COVID-19 comprises extensive or uncontrolled host immune response, manifested as
alveolar epithelial cells damage and T-cell activation in the lungs. The result is an increase in …

COVID-19: diabetes perspective—pathophysiology and management

S Dallavalasa, SRV Tulimilli, J Prakash… - Pathogens, 2023 - mdpi.com
immunity. Several hypotheses to explain the increased incidence and severity of COVID-19
clinical severity of COVID-19 in diabetics is the deregulated immune cells, leading to poor …

[HTML][HTML] COVID-19: pathophysiology, diagnosis, complications and investigational therapeutics

SA Azer - New Microbes and New Infections, 2020 - Elsevier
… The novel coronavirus (COVID-19) outbreak started early in December 2019 in the Hubei …
coronavirus-2 (SARS-CoV-2) is the most recently identified. Patients with COVID-19 may be …

Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
… A central tenet of our view on COVID-19 immunopathogenesis is that a protective immune
response must be present in patients with asymptomatic and mild infections, and even in …

Microstructure, pathophysiology, and potential therapeutics of COVID19: a comprehensive review

SP Singh, M Pritam, B Pandey… - Journal of medical …, 2021 - Wiley Online Library
… T-cell immune response is delayed and it fails to provide significant protection to COVID-19
in functional collapse of T-cell counts in COVID-19 patients. However, during recovery, …

How children are protected from COVID-19? A historical, clinical, and pathophysiological approach to address COVID-19 susceptibility

MA Massalska, HJ Gober - Frontiers in Immunology, 2021 - frontiersin.org
immune … mild COVID-19 presentation in children. Since even infants of affected mothers
are protected from the development of COVID-19, we started to believe that an adaptive immune

[PDF][PDF] Classification and pathophysiology of cutaneous manifestations of COVID-19

S Gupta, N Gupta, N Gupta - Int J Res Dermatol, 2020 - researchgate.net
COVID-19, cutaneous manifestations in COVID-19, histopathology in skin rashes of COVID-19
The trinity of COVID19: immunity, inflammation and intervention. Nat Rev Immunol. 2020: 1…

[HTML][HTML] COVID-19. Biology, pathophysiology, and immunology: a pathologist view

M Chilosi, C Doglioni, C Ravaglia, S Piciucchi… - Pathologica, 2023 - ncbi.nlm.nih.gov
… Another possible cause of innate immune deficiency in COVID-19 is the presence of anti-interferon
auto-antibodies 39-41 . Interestingly, these auto-antibodies are found in severe …

A review of pathophysiology, clinical features, and management options of COVID-19 associated coagulopathy

J Goswami, TA MacArthur, M Sridharan, RK Pruthi… - Shock, 2021 - journals.lww.com
… on laboratory coagulation disruptions associated with COVID-19 and the clinical effects of …
ischemic stroke in COVID-19. Endothelial injury and augmented innate immune response are …

COVID-19: Current Understanding of Pathophysiology

GS Shrestha, S Khanal, S Sharma, G Nepal - 2020 - 103.69.126.140
COVID -19 is based on limited data. A better understanding of disease transmission,
pathophysiology and host immune … overview of the pathophysiology of COVID-19 on various …