Covid19 and kidney injury: Pathophysiology and molecular mechanisms

E Ahmadian, SM Hosseiniyan Khatibi… - Reviews in medical …, 2021 - Wiley Online Library
… Although Covid-19 mainly targets the respiratory and immune systems, AKI is also found in
Covid-19 patients. Kidney injury and the subsequent clinical events such as haematuria and …

The immunology and immunopathology of COVID-19

M Merad, CA Blish, F Sallusto, A Iwasaki - Science, 2022 - science.org
… We review the results of almost 2 years of COVID-19 immunology research and discuss …
of COVID-19 pathophysiology. We discuss emerging understanding of differences in immune

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
… Therefore, in this study, those genetic variations mostly of encoding genes associated with
the immune responses to the COVID-19 disease predisposition or individual vulnerability …

Implications of the NADase CD38 in COVID pathophysiology

JD Zeidler, S Kashyap, KA Hogan… - Physiological …, 2022 - journals.physiology.org
… resulting from COVID-19 infection. The authors discuss a critical but underappreciated
trifecta of CD38-mediated NAD + metabolism, aging, and COVID-19 immune response and …

Cellular immunity in patients with COVID-19: molecular biology, pathophysiology, and clinical implications

SG Sсherbak, DA Vologzhanin… - Journal of Clinical …, 2022 - journals.eco-vector.com
immune responses. This review focuses on the generation and clinical significance of cellular
immunity … seasonal coronavirus-specific crossreactive T cells in response to SARS-CoV-2. …

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

Y Jamilloux, T Henry, A Belot, S Viel, M Fauter… - Autoimmunity …, 2020 - Elsevier
… to establish a more definitive view of COVID-19 pathophysiology, focusing on one key
question: “How can antiviral immunity be reinforced and hyperinflammatory damages be avoided?…

[HTML][HTML] COVID-19: infection or autoimmunity

T Icenogle - Frontiers in immunology, 2020 - frontiersin.org
… The overexuberant immune response seen in COVID-19 raises the question as to the
pathophysiology of the disease: Is the lethality related to an infection with the SARS-CoV-2 virus or …

[PDF][PDF] Pathophysiologic Enigma of COVID-19 Pandemic with Clinical Correlates

S Parveen, S Jain - International Journal of Current Research and …, 2020 - academia.edu
… Cytokine storm in COVID-19 ARDS is the commonest end event for all three identified …
Evasion of immune system Many strategies are used by Coronavirus to ensure immune …

[HTML][HTML] Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines

J Liu, J Wang, J Xu, H Xia, Y Wang, C Zhang, W Chen… - Cell Discovery, 2021 - nature.com
… previous vaccine evaluations, whether the changes in immune system function-related
genes were COVID-19-specific or could be generally applied to other vaccines or other types of …

Pathophysiology of acute respiratory syndrome coronavirus 2 infection: a systematic literature review to inform EULAR points to consider

A Najm, A Alunno, X Mariette, B Terrier, G De Marco… - RMD open, 2021 - rmdopen.bmj.com
… deleterious and aberrant host immune responses play critical roles in severe disease.
Our objective was to summarise the available information on the pathophysiology of COVID-19. …