Metabolic and immune markers for precise monitoring of COVID-19 severity and treatment

AF Rendeiro, CK Vorkas, J Krumsiek… - … in Immunology, 2022 - frontiersin.org
… -metabolic high-dimensional data, we provide novel methods for precise disease monitoring
and stratification in order to effectively tailor clinical care to COVID-19 patients. Methods

NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients

R Kircheis, E Haasbach, D Lueftenegger… - … in immunology, 2020 - frontiersin.org
… In this respect inhibiting beside phosphorylation also the following steps of IκB inactivation,
ie ubiquitination and/or proteasome degradation may provide additional treatment options. …

Why haven't we found an effective treatment for COVID-19?

AJ Spicer, S Jalkanen - Frontiers in Immunology, 2021 - frontiersin.org
… Thus, we believe that correct timing of these treatment options together with proper
thromboprophylaxis (36) is expected to improve the outcome of the COVID-19 patients. …

Abnormal immunity of non-survivors with COVID-19: predictors for mortality

Y Zhao, HX Nie, K Hu, XJ Wu, YT Zhang… - Infectious diseases of …, 2020 - Springer
… characteristics and abnormal immunity of the confirmed COVID-19 non-survivors. Methods
… , the designated hospital for treating severe patients with COVID-19 in Wuhan, China. A total …

The implications of zinc therapy in combating the COVID-19 global pandemic

N Samad, TE Sodunke, AR Abubakar… - Journal of …, 2021 - Taylor & Francis
… antiviral therapeutic option to date available for COVID-19methods because of the
harsh death toll from this novel … Immune System need to be evaluated in light of COVID-19. …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… features in COVID-19 infection, followed by normal interactions between innate immune
system and viruses, background for cytokine storm secondary to COVID-19 infection, and finally …

Combining antivirals and immunomodulators to fight COVID-19

V Feuillet, B Canard, A Trautmann - Trends in immunology, 2021 - cell.com
… We propose that efficient treatments for COVID-19 patients should … COVID-19, none shows
high potency. We posit that the innate type 1 interferon (IFNα/β)-dependent antiviral immune

[HTML][HTML] The many faces of the anti-COVID immune response

SA Vardhana, JD Wolchok - Journal of Experimental Medicine, 2020 - rupress.org
… novel therapeutic options, we offer our perspective on the anti–COVID-19 immune
response… While both innate and adaptive immune activation likely contribute to COVID-19–mediated …

Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children

P Zimmermann, N Curtis - The Pediatric infectious disease journal, 2020 - journals.lww.com
coronavirus (SARS-CoV-2) is currently causing a severe outbreak of disease (termed COVID-19)
… findings, as well as treatment and prevention options for common circulating and novel …

The ethics of COVID-19 immunity-based licenses (“immunity passports”)

G Persad, EJ Emanuel - Jama, 2020 - jamanetwork.com
… the alternatives of … COVID-19 immunity licenses can be assessed with respect to 3
fundamental ethical values: the maximization of benefit; priority to the least advantaged; and treating