[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
The recent novel coronavirus disease (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected
patients worldwide. The host immune response to SARS-CoV-2 appears to play a critical
role in disease pathogenesis and clinical manifestations. SARS-CoV-2 not only activates
antiviral immune responses, but can also cause uncontrolled inflammatory responses
characterized by marked pro-inflammatory cytokine release in patients with severe COVID …

COVID-19: Immunopathogenesis and Immunotherapeutics

U Gajbe, R Sharma, R Patil, U Gawande - ECS Transactions, 2022 - iopscience.iop.org
Introduction: The ultra-modern new coronavirus disease (COVID-19) outbreak that's
resulting from the excessive acute breathing syndrome coronavirus 2 (SARS-CoV2) is
seeing a dramatic upward thrust in inflamed people all around the world. In the aetiology
and scientific signs of SARS-CoV2, the host immune reaction seems to be crucial. In
sufferers with excessive COVID-19, SARS-CoV2 now no longer handiest turns on antiviral
immune responses, however it could additionally cause out of control inflammatory …
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