COVID-19, immune system response, hyperinflammation and repurposingantirheumatic drugs

A Tufan, AA Güler… - Turkish journal of medical …, 2020 - journals.tubitak.gov.tr
… Eventually, the exact pathophysiologic mechanism of COVID-19 remains still largely … in
COVID-19 patients [80]. Blockage of this growth factor may halt immunopathology caused by virus…

Animal models of mechanisms of SARS‐CoV‐2 infection and COVID19 pathology

SJ Cleary, SC Pitchford, RT Amison… - British journal of …, 2020 - Wiley Online Library
… key mechanisms of COVID-19 severe acute respiratory distress syndrome and the
immunopathology … -CoV-2 infection and COVID-19-related disease mechanisms and suggest …

[HTML][HTML] The immunopathology of COVID-19 and the cannabis paradigm

N Paland, A Pechkovsky, M Aswad, H Hamza… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease-19 caused by … COVID-19 symptoms are related to hyperinflammation
as seen in cytokine release syndrome and it is believed that fatalities are due to a COVID-19

[HTML][HTML] Immunogenetic association underlying severe COVID-19

K McCoy, A Peterson, Y Tian, Y Sang - Vaccines, 2020 - mdpi.com
… spectrum of COVID-19 illness could be explained by immuno-pathological regulation of …
nodes to decipher host immune mechanisms underlying the severity progression in COVID-…

COVID19-associated coagulopathy: An exploration of mechanisms

ME Colling, Y Kanthi - Vascular Medicine, 2020 - journals.sagepub.com
COVID-19 severity and mortality. We aim to review the available data on the coagulopathy
… in COVID-19 and draw from studies of prior viral epidemics to explore possible mechanisms

[HTML][HTML] The role of CD4+ FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment

Y Wang, J Zheng, MS Islam, Y Yang… - International journal of …, 2021 - ncbi.nlm.nih.gov
… The most striking immunopathology of advanced COVID-19 is cytokine release syndrome
or “cytokine storm” that is attributable to the deficiencies in immune regulatory mechanisms. …

COVID19 and immunological regulations–from basic and translational aspects to clinical implications

MP Schön, C Berking, T Biedermann… - JDDG: Journal der …, 2020 - Wiley Online Library
mechanisms in connection with SARS-CoV-2/COVID-19. … COVID-19 pandemic; some
even appear to alleviate COVID-… patients from COVID-19-associated immunopathology, as …

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

Y Zhou, B Fu, X Zheng, D Wang, C Zhao… - National Science …, 2020 - academic.oup.com
… It is urgent to identify the immunopathology mechanism to delay the pulmonary immune …
curb immunopathology caused by COVID-19. The study provides a detailed immunopathology

[HTML][HTML] Current approaches used in treating COVID-19 from a molecular mechanisms and immune response perspective

A Alnefaie, S Albogami - Saudi Pharmaceutical Journal, 2020 - Elsevier
… Furthermore, we review drugs targeting COVID-19 that are under investigation and in …
updates on COVID-19 vaccine development. Understanding the molecular mechanisms of how …

[HTML][HTML] Histomorphological patterns of regional lymph nodes in COVID-19 lungs

JD Haslbauer, MS Matter, AK Stalder, A Tzankov - Der Pathologe, 2021 - Springer
… Histomorphological patterns in lymph nodes [42] may provide valuable insights into the
immunopathological mechanisms of disease. They reflect complex interactions between antigens…