… all aspects of COVID-19 therapeutics. We explore challenges that have stymied COVID-19
drug development and highlight important unmet needs. We examine key therapeutic classes …

… therapeutics against SARS-CoV-19. We intend for this review to familiarize readers with the
toxicities of potential therapeutics for COVID-19 … knowledge of novel therapeutics as publicly …

… Coronavirus disease of 2019 (COVID-19) is caused by the severe acute respiratory syndrome
coronavirus … million confirmed worldwide cases of COVID-19 with over 375,000 deaths [2]. …

… The complex virology of COVID-19 may provide multiple potential target points for antiviral
… against COVID-19, which we highlight, again with varying results. In addition to therapeutics, …

… Therapeutic strategy based on viral kinetics and immunopathogenesis during the course of
coronavirus … Because COVID-19 is caused by SARS-CoV-2, the core therapeutic strategy …

… -RNAs could potentially alleviate complications from COVID-19. Here, we will review … in
COVID-19 pathogenicity and immune response. Then, we focus on potential miRNA therapeutics …

… its mode of infection, the pathophysiology of COVID-19, the epidemiology of the disease and
… virus and COVID-19 and in so doing to ascertain the implications for therapeutic intervention…

… anti-coronavirus activities. We also discuss the lessons learned from COVID-19 and other
infectious diseases with regard to drug repurposing strategies, pan-coronavirus drug targets, …

… responses and COVID-19 disease trajectory, we stratified the 71 COVID-19 patients into …
ranging from COVID 1 (death) and COVID 2 (requiring maximal clinical intervention) to COVID 8 …

… on the important therapeutic implications of COVID-19 for … presentations seen in COVID-19
positive patients and the … in patients with COVID-19 and acute coronary syndromes. …