Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
regulation between protective and altered responses due to exacerbation of the inflammatory
… investigation to further understand COVID-19 immunopathogenesis, thus helping to design …

COVID-19 cytokine storm: The anger of inflammation

M Mahmudpour, J Roozbeh, M Keshavarz, S Farrokhi… - Cytokine, 2020 - Elsevier
inflammatory cytokine overproduction are addressed in this work. The virus-mediated
down-regulation of ACE2 causes a burst of inflammatory … and treat COVID-19 associated acute …

[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
… causative agent of coronavirus disease-19 (COVID-19), an … severe COVID-19 disease
induced by SARS-CoV-2 coronavirusCOVID-19 patients through the inhibition of pro-inflammatory

Targeting MMP-regulation of inflammation to increase metabolic tolerance to COVID-19 pathologies: a hypothesis

E Hardy, C Fernandez-Patron - Biomolecules, 2021 - mdpi.com
… in the development of COVID-19 and postulate a mechanism … in the levels of MMPs in
COVID-19 patients, along with the … influence host tolerance against COVID-19 and, perhaps also…

Inflammatory pathways in COVID19: mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
COVID-19. Here, we discuss the major inflammatory pathways in the pathogenesis of
COVID-19, … understanding of the regulatory pathways of COVID-19 immune dysregulation and …

Compartmentalized Regulation of Pulmonary and Systemic Inflammation in Critical COVID-19 Patients

L Santiago, MH Gonçalves-Pereira, MS Vieira… - Viruses, 2023 - mdpi.com
… can lead to multiorgan dysfunction in critical COVID-19 [6,30,31], … inflammation in both sites.
Therefore, studying the systemic and pulmonary inflammatory response in critical COVID-19

MS-based targeted profiling of oxylipins in COVID-19: A new insight into inflammation regulation

D Biagini, M Franzini, P Oliveri, T Lomonaco… - Free Radical Biology …, 2022 - Elsevier
… of 48 oxylipins and 5 cytokines in COVID-19 ward and ICU patients were … inflammatory
process are proposed, shedding new light on the pathophysiological mechanism of the COVID-19

… illustrates the immune regulation, anti-infection, anti-inflammation, and multi-organ protection mechanism of Qing-Fei-Pai-Du decoction in the treatment of COVID-19

J Zhao, S Tian, D Lu, J Yang, H Zeng, F Zhang, D Tu… - Phytomedicine, 2021 - Elsevier
… basis for our better understanding of the mechanism of QFPDD's treatment on COVID-19. …
to treat COVID-19. Following extensive data mining, we collected a list of COVID-19 related …

Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19

YY Yong, L Zhang, YJ Hu, JM Wu, L Yan, YR Pan… - Clinical …, 2022 - Elsevier
… lung inflammation at the late stage of COVID-19. Here, we discuss the autophagy regulation
at different stages of COVID-19… of autophagy activators in COVID-19 by inhibiting the NLRP3 …

[HTML][HTML] The Society for Immunotherapy of Cancer perspective on regulation of interleukin-6 signaling in COVID-19-related systemic inflammatory response

FI Arnaldez, SJ O'Day, CG Drake, BA Fox… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
… profound inflammatory state seen in patients with COVID-19 … for critically ill patients with
COVID-19 with the administration of … pathological inflammation seen in patients with COVID-19. …