… milder cell-mediated immune response and milder inflammation than in adults. Actually, the
… patients and minimize the damaging effect of inflammatory pneumonia. One of the possible …

… the nuclear factor kappa B (NF-κB) pathway and stimulated by the simultaneous activation of
IL-… in COVID-19, because IL-6 is a major STAT3 stimulator, particularly during inflammation. …

… Based on the facts and current COVID-19 scenario, the inhibition of the NF-κB signalling
pathway as a therapeutic intervention seems to be an inevitable hypothesis for future studies. …

… of COVID-19 disease severity. In this review, we highlight prominent cytokine families and
their potential role in COVID-19, … pathways are activated leading to type I/II Interferons and pro-…

… Fibrinogen has been identified as a risk factor as well as modulator of inflammatory pathways
in several infectious diseases. It is a soluble glycoprotein 340-KDa synthesized in liver by …

… Covid-19, as well as upregulated inflammatory responses, and their effects on alveolar integrity
require further study. Autopsy results of a Covid-19 … inflammatory cytokines or pathways …

… by TXA 2 ), which is also akin to effects of the PGE 2 – EP4 receptor pathway. The ability
of PGI 2 to regulate immune and inflammatory responses thus has implications for COVID-19. …

… T cell activation may have helped the inflammatory response by the IL-1 pathway, while
in the other two cases the low inflammatory response allowed a moderate T cell response. …

… We focus on the role of the nicotinic cholinergic system in COVID-19 and the association
between nAchRalpha7 and its protective role in inflammation via the IRAK-M pathway. …

… The drug as a theoretical perspective may be an effective and safe choice for suppressing
the inflammatory response during COVID-19. The recommendation would be a combination of …