COVID-19 as an acute inflammatory disease

RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
coronavirus disease (COVID-19) pandemic caused by the virus severe acute respiratory
syndrome coronavirus… threatening inflammatory responses during sepsis, trauma, or COVID-19. …

[HTML][HTML] Pattern of inflammatory immune response determines the clinical course and outcome of COVID-19: unbiased clustering analysis

EE Lee, KH Song, W Hwang, SY Ham, H Jeong… - Scientific reports, 2021 - nature.com
… patterns in inflammatory immune responses of COVID-19 patients … Data from hospitalized
COVID-19 patients were retrieved … of inflammatory responses in those with COVID-19 infection …

[HTML][HTML] Overview: systemic inflammatory response derived from lung injury caused by SARS-CoV-2 infection explains severe outcomes in COVID-19

RB Polidoro, RS Hagan, R de Santis Santiago… - Frontiers in …, 2020 - frontiersin.org
inflammatory response syndrome” or SIRS (26). To address an overview of how a similar
process might be at play with COVID-19 … infection, (2) COVID-19 associated lung injury (CALI; …

[HTML][HTML] Lessons learned from the mechanisms of posttraumatic inflammation extrapolated to the inflammatory response in COVID-19: a review

MPJ Teuben, R Pfeifer, H Teuber, LL De Boer… - Patient safety in …, 2020 - Springer
COVID-19 infection, secondary insults or complications may stimulate an exaggerated immune
response, amplify systemic inflammationinflammatory disease progression in COVID-19, …

[HTML][HTML] Immune-mediated inflammatory responses of alveolar epithelial cells: Implications for COVID-19 lung pathology

A Barilli, R Visigalli, F Ferrari, MG Bianchi, V Dall'Asta… - Biomedicines, 2022 - mdpi.com
… disease in COVID-19. However, the pathogenic mechanisms underlying COVID-19-associated …
This study aims to explore the inflammatory responses of alveolar epithelial cells to either …

[HTML][HTML] Comparison of host endothelial, epithelial and inflammatory response in ICU patients with and without COVID-19: a prospective observational cohort study

PK Bhatraju, ED Morrell, L Zelnick, NA Sathe, XY Chai… - Critical Care, 2021 - Springer
… between COVID-19 and non-COVID-19 patients, we used linear regression with robust
Huber-White standard errors of the log-transformed plasma biomarker on COVID-19 status. …

[HTML][HTML] Is there a crucial link between vitamin D status and inflammatory response in patients with COVID-19?

F Saponaro, M Franzini, C Okoye, R Antognoli… - Frontiers in …, 2022 - frontiersin.org
… In conclusion, the present study focuses on the link between vitamin D and inflammatory
response, which is in turn correlated with the severity of COVID-19. The observed relationship …

[HTML][HTML] Pulmonary inflammatory response in lethal COVID-19 reveals potential therapeutic targets and drugs in phases III/IV clinical trials

A López-Cortés, S Guerrero, E Ortiz-Prado… - Frontiers in …, 2022 - frontiersin.org
… stage COVID-19 clinical trials. Results: Herein, we analyzed transcriptomics data of 719
inflammatory response genes across 19 … were inflammatory response, innate immune response, …

Comprehensive Analysis of the Systemic Transcriptomic Alternations and Inflammatory Response during the Occurrence and Progress of COVID19

S Mo, L Dai, Y Wang, B Song, Z Yang… - Oxidative Medicine and …, 2021 - Wiley Online Library
… the signature of the peripheral blood of COVID-19. Various immune cells were … inflammatory
response and the disease course, which provided strategies for the treatment of COVID-19

COVID-19 and multiorgan response

S Zaim, JH Chong, V Sankaranarayanan… - Current problems in …, 2020 - Elsevier
… in COVID-19 patients could be due to kidney-lung crosstalk 76 for the following reasons:
renal cells have the potential to be target sites for SARS-CoV-2 and inflammatory responses