Natural killer cell immunotypes related to COVID-19 disease severity

…, Karolinska COVID-19 Study Group - Science …, 2020 - science.org
… of NK cells in patients with moderate and severe COVID-19 … with moderate and severe
COVID-19 disease were recruited … NK cell activation, education, and presence of adaptive NK cells

Natural killer cell dysfunction and its role in COVID-19

C van Eeden, L Khan, MS Osman… - International journal of …, 2020 - mdpi.com
cells (CD57 + ), and an increased CD56 DIM :CD56 BRIGHT ratio. The increase in CD56
DIM cells may be compensatory to the loss of natural killer cell … in our fight against COVID-19. …

Defining the role of natural killer cells in COVID-19

MJ Lee, CA Blish - Nature immunology, 2023 - nature.com
… to NK cells in COVID-19. We discuss the impacts of COVID-19 on host NK cell phenotype
and … and hypofunctional profile of these cells. We enumerate the changes induced in infected …

[HTML][HTML] Natural killer cells and unconventional T cells in COVID-19

NK Björkström, A Ponzetta - Current Opinion in Virology, 2021 - Elsevier
coronavirus disease 2019 (COVID-19) [3]. In this Review, current knowledge of antiviral
responses of natural killer (NK) cells and unconventional T cells … on the role of these cells in the …

Natural killer cell activation related to clinical outcome of COVID-19

…, NK Björkström, Karolinska COVID-19 Study Group - medRxiv, 2020 - medrxiv.org
… between NK cell activation, T cellcells in patients with moderate and severe COVID-19
disease. With strict inclusion and exclusion criteria, patients with moderate and severe COVID-19

Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19

O Demaria, J Carvelli, L Batista, ML Thibult… - Cellular & molecular …, 2020 - nature.com
19, to enhance NK cell-mediated viral clearance. We therefore analyzed whether NK cells
from COVID-19 … We found that NK cells isolated from the blood of ARDS COVID-19 patients …

Impaired natural killer cell counts and cytolytic activity in patients with severe COVID-19

M Osman, RM Faridi, W Sligl, MT Shabani-Rad… - Blood …, 2020 - ashpublications.org
… Our findings suggest that impaired counts and cytolytic activity of NK cells are important
characteristics of severe COVID-19 and can potentially facilitate strategies for …

Natural killer cells in COVID-19: from infection, to vaccination and therapy

A Zafarani, MH Razizadeh, S Pashangzadeh… - Future …, 2023 - Taylor & Francis
cells that fight against infected cells. The function of these cells is impaired in patients with
COVID-19 … the disease or destroy the infected cells. Few studies have evaluated the effects of …

Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020

C Manickam, S Sugawara, RK Reeves - PLoS pathogens, 2020 - journals.plos.org
COVID-19 patients with severe pneumonia [19]. While there is limited data available on the
role of NK cells in COVID-19 … exhaustion of NK cells and T cells could further complicate the …

Flattening the COVID-19 curve with natural killer cell based immunotherapies

M Market, L Angka, AB Martel, D Bastin… - Frontiers in …, 2020 - frontiersin.org
cells respond in both early and late coronavirus infections, and the implication for ongoing
COVID-19 … recommendations for therapeutic strategies against COVID-19 in clearing the virus …